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Key Documents

AQ502P

Sigma-Aldrich

Goat Anti-Mouse IgM+IgG+IgA Antibody, F(ab′)2, HRP conjugate, Species Adsorbed

Chemicon®, from goat

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.46

生物源

goat

品質等級

共軛

peroxidase conjugate

抗體表格

purified antibody

抗體產品種類

secondary antibodies

無性繁殖

polyclonal

物種活性

mouse

製造商/商標名

Chemicon®

技術

ELISA: suitable

運輸包裝

wet ice

目標翻譯後修改

unmodified

一般說明

IgG is the most abundant immunoglobulin and comprises two heavy chains and two light chains. Each molecule has two antigen binding sites. IgG has 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). IgM constitutes about 10% of serum immunoglobulins. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces.

特異性

Reacts with heavy and light chains of mouse IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA. Absorbed for human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins.
The antibody reacts with the heavy and light chains of mouse IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.

免疫原

Epitope: Mouse IgM, IgG, IgA
Prepared from pepsin digest of mouse Ig (H+L).

應用

ELISA: 1:4,000-1:8,000.

Optimal working dilutions must be determined by the end user.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies
This Goat anti-Mouse IgM+IgG+IgA Antibody, F(ab′)2, HRP conjugate, Species Adsorbed is validated for use in ELISA for the detection of Mouse IgM+IgG+IgA.

外觀

Gel filtration chromatography
Purified by gel filtration chromatography of pepsin digested antibody. Liquid in 50% glycerol/50% PBS, pH 7.4.

儲存和穩定性

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. For long term storage, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2


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John E La Marca et al.
International journal of molecular sciences, 22(23) (2021-12-11)
Tissue homeostasis via the elimination of aberrant cells is fundamental for organism survival. Cell competition is a key homeostatic mechanism, contributing to the recognition and elimination of aberrant cells, preventing their malignant progression and the development of tumors. Here, using

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