ABT42

Anti-Myosin-VI Antibody

from rabbit, purified by affinity chromatography

• 别名: Myosin-VI, Unconventional myosin-6
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: canine, human, mouse
• 物種活性（以同源性預測）: rat (based on 100% sequence homology)
• 技術: immunocytochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_004990
• UniProt登錄號: Q9UM54
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MYO6(4646)

说明

一般說明

Myosin-VI has been found in the membrane ruffles at the leading edge of the Golgi complex. Myosin-VI moves along the actin in the opposite way of other known myosins to date, toward the minus end. It can exist as a dimer and a monomer and is thought to function as a non-processive motor with a 18nm working stroke. Myosin-VI has also been found in the brain, specifically the synapses. Myosin-VI deficiency (Snell’s waltzer disease) in the hippocampus causes a smaller number of synapses, short dendritic spines and astrogliosis. Myosin-VI may also be important in clathrin-mediated endocytosis of acid-type glutamate receptors. Recent research has implicated myosin-VI in the enrichment of proteins on the surface of axons.

免疫原

KLH-conjugated linear peptide corresponding to human Myosin-VI.

應用

Anti-Myosin-VI Antibody detects level of Myosin-VI & has been published & validated for use in WB & IC.

Immunocytochemistry analysis: A 1:500 dilution from a representative lot detected Myosin-VI in NIH/3T3 and A431 cells.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

品質

Evaluated by Western Blot in MDCK cell lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Myosin-VI in 10 µg of MDCK cell lysate.

標靶描述

~150 kDa observed.
An uncharacterized band appears at ~55 kDa in some lysates.

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
MDCK cell lysate

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable