ABC829

Anti-SCRN1 Antibody

from rabbit, purified by affinity chromatography

• 别名: Secernin-1, SCRN1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 無性繁殖: polyclonal
• application: IF; IHC; WB
• 物種活性: human
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProt登錄號: Q12765
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SCRN1(9805)

说明

一般說明

Secernin-1 (SCRN1) is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.

免疫原

Epitope: C-terminus

KLH-conjugated synthetic peptide corresponding to the C-terminus of human SCRN1.

應用

Anti-SCRN1 Antibody is an antibody against SCRN1 for use in western blotting, IHC & immunofluorescence.

Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected SCRN1 in human kidney tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected SCRN1 in human kidney cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

品質

Evaluated by Western Blotting in human kidney tissue with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected SCRN1 in human kidney tissue with and without blocking peptide.

標靶描述

~30 and ~48 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外觀

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable