ABC304

Anti-Olfactomedin-4/OLFM4 Antibody

from rabbit, purified by affinity chromatography

• 别名: Olfactomedin-4, OLM4, Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein, hGC-1, hOLfD
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunohistochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_006409
• UniProt登錄號: Q6UX06
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... OLFM4(10562)

说明

一般說明

OLFM4, also known as Olfactomedin-4, Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein (hGC-1), or hOLfD, and encoded by the gene OLFM4/GW112 is a multimeric protein that has been found both extracellularly, interacting with cell surface lectins and cadherin proteins, and intracellularly within the mitochondria and cytoplasm. OLFM4 is expressed during myeloid lineage development but also in found in adult prostate, bone marrow, and stomach, as well as pancreatic cancer cells. The protein appears to govern cell proliferation in pancreatic cancer cells however in leukemic cell lines it inhibits cell growth and induces cell differentiation and apoptosis. The gene is induced by retinoic acid contact and signaling is linked via the NFkappaB pathway.

免疫原

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human Olfactomedin-4/OLFM4.

應用

Anti-Olfactomedin-4/OLFM4 Antibody is an antibody against Olfactomedin-4/OLFM4 for use in western blotting & IHC.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Olfactomedin-4/OLFM4 in 10 µg of human liver tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Olfactomedin-4/OLFM4 in human pancreatic cancer sections and human prostate tissue.

品質

Evaluated by Western Blotting in human small intestine tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Olfactomedin-4/OLFM4 in 10 µg of human small intestine tissue lysate.

標靶描述

~64 kDa observed. The calculated molecular weight of this protein is 57 kDa, but can be observed at ~64 kDa due to high glycosylation.

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable