AB9872

Anti-TrkB Antibody

serum, Chemicon^®

• 别名: Tyrosine kinase receptor B
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: serum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: mouse, rat
• 製造商／商標名: Chemicon^®
• 技術: immunohistochemistry: suitable
• NCBI登錄號: NM_001007097.1; NM_001018064.1; NM_001018065.1; NM_001018066.1; NM_006180.3
• UniProt登錄號: Q16620
• 運輸包裝: dry ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NTRK2(4915)

说明

一般說明

The mammalian Trk family of receptor tyrosine kinases consists of three principle transmembrane proteins. The receptors can be activated by one or more of four neurotrophins - NGF, BDNF, NT3 and NT4/5. The TrkB family of transmembrane proteins serves as receptors for BDNF and NT-4/5 and these neurotrophins regulate biological responses such as cell survivial, proliferation and differentiation in normal and neoplastic neuronal cells.

特異性

Other species have not yet been tested. It is expected to react with a wide range of mammalian species, based on the high sequence similarity.

trkB [BDNF/NT-4/5 growth factor receptor; tyrosine kinase receptor B]. The immunogen sequence was chosen to avoid cross reactivity with trkA or trkC.

免疫原

Extracellular domain of the recombinant mouse receptor expressed in mammalian cells.

應用

Anti-TrkB Antibody is an antibody against TrkB for use in IH.

Immunohistochemistry: 1:3,000. The antibody has been used successfully on rat dorsal root ganglion and trigeminal ganglia in the rat spinal cord (cryostat free-floating sections). Suggested fixative is 4% paraformaldehyde.

Not suitable for Western blot.

Optimal working dilutions must be determined by end user.

Research Category
Neuroscience

Research Sub Category
Neurochemistry & Neurotrophins

外觀

Serum

Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

儲存和穩定性

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable