生物源
rabbit
品質等級
抗體表格
affinity purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
polyclonal
純化經由
affinity chromatography
物種活性
rat
製造商／商標名
Chemicon®
技術
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
phosphorylation (pTyr1336)
基因資訊
rat ... Grin2B(24410)
特異性
NMDAR2B, phosphoTyrosine1336. The antibody recognizes a protein of ~180 kDa corresponding to NMDAR2B, phosphoTyrosine1336 in lysates from rat brain hippocampus. Immunolabeling is blocked by the phosphopeptide used as the immunogen but not the corresponding non-phosphopeptide. Immunolabeling is also blocked by l-phosphatase treatment.
免疫原
Synthetic peptide of amino acids surrounding the phosphoTyrosine 1336 site of rat NMDAR2B. The immunogen has 100% similarity with human and mouse.
應用
Detect NMDAR2B phospho Tyrosine 1336 using this Anti-NMDAR2B phospho Tyrosine 1336 Antibody validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blot: 1:1,000.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
聯結
Replaces: 07-533
外觀
Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.
儲存和穩定性
Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity.
Carroll, Reed C and Zukin, R Suzanne
Trends in Neurosciences, 25, 571-577 (2002)
D R Grosshans et al.
Nature neuroscience, 5(1), 27-33 (2001-12-12)
In the CA1 region of the rat hippocampus, long-term potentiation (LTP) requires the activation of NMDA receptors (NMDARs) and leads to an enhancement of AMPA receptor (AMPAR) function. In neonatal hippocampus, this increase in synaptic strength seems to be mediated
Jérémy Ferrier et al.
PloS one, 8(10), e77828-e77828 (2013-11-10)
Oxaliplatin is an anticancer drug used for the treatment of advanced colorectal cancer, but it can also cause painful peripheral neuropathies. The pathophysiology of these neuropathies has not been yet fully elucidated, but may involve spinal N-methyl-D-aspartate (NMDA) receptors, particularly
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