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Merck
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主要文件

AB770

Sigma-Aldrich

Anti-TIMP-1 Antibody

Chemicon®, from rabbit

别名:

Tissue Inhibitor of Metalloproteinase-1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

bovine, rat, ferret, sheep, horse, rabbit

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... TIMP1(7076)

特異性

Reacts with TIMP1. Does not react with any other human proteins tested so far. The antibody reacts with native and denatured TIMP1 and TIMP1 in and out of enzyme/inhibitor complex.

免疫原

Full length purified human fibroblast tissue inhibitor of metalloproteinases {Clark, IM (1991) Matrix 11:76-85}.

應用

Anti-TIMP-1 Antibody detects level of TIMP-1 & has been published & validated for use in ELISA, WB, IH.
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs
Western Blotting at 5-10 μg/mL: recognizes a band of approximately 28-30kDa in reduced samples.

Immunohistochemistry: frozen and 4%PFA fixed paraffin sections: 5-20μg/mL enzymatic detection.



Optimal working dilutions must be determined by end user.

聯結

Replaces: 04-1133

外觀

Purified immunoglobulin. Liquid in PBS containing 0.02% azide.

儲存和穩定性

Maintain refrigerated at 2-8°C for up to three months from date of receipt. For extended storage, freeze in convenient undiluted aliquots at -20°C for up to twelve months from date of receipt. Avoid repeated freeze/thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Renal connective tissue growth factor correlates with glomerular basement membrane thickness and prospective albuminuria in a non-human primate model of diabetes: possible predictive marker for incipient diabetic nephropathy.
Sally E Thomson,Susan V McLennan,Paul D Kirwan,Scott J Heffernan,Annemarie Hennessy et al.
Journal of Diabetes and Its Complications null
Polyclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunosorbent assay to measure TIMP-collagenase complex.
Clark, I M, et al.
Matrix, 12, 108-115 (1992)
T A Plumpton et al.
Clinica chimica acta; international journal of clinical chemistry, 240(2), 137-154 (1995-09-15)
A panel of six monoclonal antibodies (MAbs) was raised against purified human fibroblast tissue inhibitor of metalloproteinase-1 (TIMP-1) and characterised. All possible antibody pairs were tested for their suitability as capture and revealing antibodies in a two-site enzyme-linked immunosorbent assay
Polyclonal and monoclonal antibodies against human tissue inhibitor of metalloproteinases (TIMP) and the design of an enzyme-linked immunosorbent assay to measure TIMP
Clark, I M, et al
Matrix, 11, 76-85 (1991)
Monoclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunosorbent assay to measure total collagenase
Clark, I M, et al
Matrix, 12, 475-480 (1992)

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