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Merck
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Key Documents

AB5370

Sigma-Aldrich

Anti-Capsaicin Receptor Antibody, CT

serum, Chemicon®

别名:

Vanilloid Receptor 1, VR1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, human

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... TRPV1(7442)

特異性

Capsaicin Receptor (Vanilloid Receptor 1, VR1).

免疫原

A 21 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein.
Epitope: C-terminus

應用

Detect Capsaicin Receptor using this Anti-Capsaicin Receptor Antibody, C-terminus validated for use in IH.
Immunohistochemistry: 1:2,000. The antibody reacts well with tissue from the rat dorsal root ganglia.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neuroinflammation & Pain

Neurotransmitters & Receptors

外觀

Serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.

儲存和穩定性

Maintain lyophilized material at -20°C to -70°C for up to 6 months. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Emily M Besecker et al.
Experimental neurology, 323, 113092-113092 (2019-11-08)
Dramatic impairment of gastrointestinal (GI) function accompanies high-thoracic spinal cord injury (T3-SCI). The vagus nerve contains mechano- and chemosensory fibers as well as the motor fibers necessary for the central nervous system (CNS) control of GI reflexes. Cell bodies for
Distribution and function of the cannabinoid-1 receptor in the modulation of ion transport in the guinea pig ileum: relationship to capsaicin-sensitive nerves.
Wallace K MacNaughton, Marja D Van Sickle, Catherine M Keenan, Kelly Cushing, Ken Mackie et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology null
TRPV1 receptor signaling mediates afferent nerve sensitization during colitis-induced motility disorders in rats.
De Schepper, HU; De Man, JG; Ruyssers, NE; Deiteren, A; Van Nassauw, L; Timmermans et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology null
Parvalbumin and TRPV1 receptor expression in dorsal root ganglion neurons after acute peripheral inflammation.
G Zacharova, J Palecek, G Zacharova, J Palecek, G Zacharova, J Palecek
Physiological Research null
H U De Schepper et al.
The Journal of physiology, 586(21), 5247-5258 (2008-08-30)
Patients with inflammatory bowel disease often suffer from gastrointestinal motility and sensitivity disorders. The aim of the current study was to investigate the role of transient receptor potential of the vanilloid type 1 (TRPV1) receptors in the pathophysiology of colitis-induced

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