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Key Documents

AB3530P

Sigma-Aldrich

Anti-Epithelial Sodium Channel-α Antibody

Chemicon®, from rabbit

别名:

ENaC-alpha

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rat

製造商/商標名

Chemicon®

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... SCNN1A(6337)

特異性

Recognizes rat Epithelial Sodium Channel alpha (ENaC alpha). The immunogen shows no significant sequence homology with other ENaC subunits.

免疫原

A 20 amino acid peptide sequence near the N-terminus of rat ENaC alpha (Linguela et al. 1993; Canessa et al.

1993; Snyder et al. 1994; Waldmann et al. 1995; Kreutz et al. 1997; Voilley et al.

1994; McDonald et al. 1994; Ludwig et al. 1998; Garty & Palmer 1997).

應用

Anti-Epithelial Sodium Channel-α Antibody is an antibody against Epithelial Sodium Channel-α for use in WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Neuroinflammation & Pain
Western blot: 1-10 μg/mL using ECL and rat brain membrane preparations, see membrane preparation protocol under Technical Support\General Technical Info\General Methods at www.chemicon.com.

83-90kDa band is expected.

Optimal working dilutions must be determined by the end user.

標靶描述

83-90kDa

外觀

ImmunoAffinity Purified
Affinity Purified immunoglobulin. Liquid in phosphate buffered saline, pH 7.4, containing 0.1% BSA and 0.1% sodium azide.

儲存和穩定性

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析報告

Control
Epithelial structures

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Estrogen increases ENaC activity via PKC? signaling in renal cortical collecting duct cells.
Yusef, YR; Thomas, W; Harvey, BJ
Physiological Reports null
Expression of water and ion transporters in tracheal aspirates from neonates with respiratory distress.
Li Y, Marcoux MO, Gineste M, Vanpee M, Zelenina M, Casper C
Acta Paediatrica (Oslo, Norway : 1992) null
L R E Pedersen et al.
Acta physiologica (Oxford, England), 206(2), 142-149 (2012-06-12)
We wished to determine the effect of continuous β-receptor stimulation on alveolar fluid clearance and to elucidate the mechanisms behind this effect. Alveolar fluid clearance was measured in anaesthetized rats pretreated for 72 h with the β-agonist isoproterenol (200 μg kg(-1) h(-1) sc)
Takahiro Masuda et al.
American journal of physiology. Renal physiology, 315(3), F653-F664 (2018-05-24)
The chronic intrinsic diuretic and natriuretic tone of sodium-glucose cotransporter 2 (SGLT2) inhibitors is incompletely understood because their effect on body fluid volume (BFV) has not been fully evaluated and because they often increase food and fluid intake at the

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