生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human, mouse, rat
技術
western blot: suitable
GenBank登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Per1(18626)
一般說明
该基因是Period基因家族的成员，并在视交叉上核（哺乳动物脑中的主要昼夜节律起搏器）中以昼夜节律模式表达。该家族中的基因编码运动活动，代谢和行为的昼夜节律的组成部分。视交叉上核中的昼夜节律表达在恒定的黑暗中继续进行，并且明/暗周期的变化引起视交叉上核中基因表达的比例变化。该基因的特定功能尚不清楚。在该基因中观察到了选择性剪接。但是，这些变体尚未得到充分描述。
特異性
基于序列同源性，可能与果蝇、尼罗罗非鱼和黄金仓鼠反应。 与其他物种的反应性尚未得到测试。
目录#AB2201将识别mPer1的N端。
應用
使用经验证可用于WB的抗mPER1（残基6-21）抗体检测mPER1（残基6-21）。
免疫组化：
在全脑上进行了测试（SCN；CT/ZT12的峰值染色）。 需要根据最终使用情况确定最佳工作稀释度。
在全脑上进行了测试（SCN；CT/ZT12的峰值染色）。 需要根据最终使用情况确定最佳工作稀释度。
品質
通过蛋白质印迹法对人脑裂解液进行常规测试
標靶描述
136 kDa
法律資訊
GenBank is a registered trademark of United States Department of Health and Human Services
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Circadian key component CLOCK/BMAL1 interferes with segmentation clock in mouse embryonic organoids.
Yasuhiro Umemura et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(1) (2021-12-22)
In mammals, circadian clocks are strictly suppressed during early embryonic stages, as well as in pluripotent stem cells, by the lack of CLOCK/BMAL1-mediated circadian feedback loops. During ontogenesis, the innate circadian clocks emerge gradually at a late developmental stage, and
D Shuboni et al.
Neuroscience, 170(4), 1172-1178 (2010-08-14)
The daily light dark cycle is the most salient entraining factor for the circadian system. However, in modern society, darkness at night is vanishing as light pollution steadily increases. The impact of brighter nights on wild life ecology and human
G Leach et al.
Neuroscience, 234, 31-39 (2013-01-15)
Seasonal affective disorder (SAD) is a major depressive disorder that recurs in the fall and winter when day-length gets short. It is well accepted that day-length is encoded by the principal circadian clock located in the suprachiasmatic nucleus (SCN), but
Rapid resetting of the mammalian circadian clock.
Best, J D, et al.
The Journal of Neuroscience, 19, 828-835 (1999)
Tomoko Ikeno et al.
Journal of biological rhythms, 31(4), 352-364 (2016-04-15)
In mammals, the circadian system is composed of a principal circadian oscillator located in the suprachiasmatic nucleus (SCN) and a number of subordinate oscillators in extra-SCN brain regions and peripheral tissues/organs. However, how the time-keeping functions of this multiple oscillator
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