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品質等級
產品線
Novabiochem®
形狀
powder
反應適用性
reaction type: Fmoc solid-phase peptide synthesis
製造商／商標名
Novabiochem®
應用
peptide synthesis
官能基
sulfonic acid
儲存溫度
15-25°C
一般說明
Introduction of 4-sulfo-phenylalanine is an effective strategy for increasing solubility of a peptide. This amino acid has also been employed in analogs of angiotensin 2 [1], phytosulfokine [2], and cyclolinopeptide A [3]. Its incorporation during solid phase synthesis using Fmoc-Phe(SO3Na)-OH is best carried out with base-mediated coupling methods such as PyBOP® or HBTU.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] E. Escher, et al. (1983) , 66, 1355.
[2] A. Bahyrycz, et al. (2004) , 10, 462.
[3] Y. Fujiwara, et al. (1994) , 42, 724.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] E. Escher, et al. (1983) , 66, 1355.
[2] A. Bahyrycz, et al. (2004) , 10, 462.
[3] Y. Fujiwara, et al. (1994) , 42, 724.
分析報告
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -17.0 - -15.0 °
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Purity TLC (BAW 1): ≥ 97.0 %
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -17.0 - -15.0 °
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Purity TLC (BAW 1): ≥ 97.0 %
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
法律資訊
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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