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品質等級
產品線
Novabiochem®
形狀
powder
反應適用性
reaction type: Fmoc solid-phase peptide synthesis
製造商／商標名
Novabiochem®
應用
peptide synthesis
官能基
amine
儲存溫度
2-8°C
InChI
1S/C27H34N2O6/c1-27(2,3)35-25(32)28-16-10-4-5-15-23(24(30)31)29-26(33)34-17-22-20-13-8-6-11-18(20)19-12-7-9-14-21(19)22/h6-9,11-14,22-23H,4-5,10,15-17H2,1-3H3,(H,28,32)(H,29,33)(H,30,31)/t23-/m0/s1
InChI 密鑰
CLFMIWUWBOOJLY-QHCPKHFHSA-N
一般說明
This homolog of lysine has been used to modulate ion-pairing interactions between Lys and enzyme carboxylate groups in SAR studies [1].
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] K. J. Kennedy, et al. (1997) Bioorg. Med. Chem. Lett., 7, 1937.
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Literature references
[1] K. J. Kennedy, et al. (1997) Bioorg. Med. Chem. Lett., 7, 1937.
應用
Fmoc-hLys(Boc)-OH can be used as a building block in the solid phase peptide synthesis.
分析報告
Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
To see the solvent systems used for TLC of Novabiochem® products please click here.
法律資訊
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Probing the flexibility of the catalytic nucleophile in the lyase catalytic pocket of human DNA polymerase β with unnatural lysine analogues
Daskalova SM, et al.
Biochemistry, 56(3), 500-513 (2017)
Exploring the impact of the side-chain length on peptide/RNA binding events
Sbicca L, et al.
Physical Chemistry Chemical Physics, 19(28), 18452-18460 (2017)
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