8.52113

Fmoc-Asp(biotinyl-PEG)-OH

Novabiochem^®

• 别名: Fmoc-Asp(biotinyl-PEG)-OH, N-α-Fmoc-N-γ-(N-biotinyl-3-(2-(2-(3-aminopropyloxy)-ethoxy)-ethoxy)-propyl)-L-asparagine
• 经验公式（希尔记法）: C₃₉H₅₃N₅O₁₀S
• 分子量: 783.93
• 分類程式碼代碼: 12352209
• NACRES: NA.22

属性

• 品質等級: 200
• 產品線: Novabiochem^®
• 化驗: ≥95.0% (HPLC); ≥98% (TLC)
• 形狀: powder
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 官能基: biotin
• 儲存溫度: 2-8°C

说明

一般說明

In contrast to Fmoc-Lys(biotin)-OH, this novel biotin-labeled amino acid has excellent solubility in DMF and other solvents used in Fmoc SPPS ^[1]. The PEG-spacer restricts hindrance between the peptide and avidin, leading to better biotin binding. Furthermore, the hydrophilic nature of the PEG minimizes non-specific interactions that can arise from the spacer group becoming buried in the hydrophobic pocket of proteins.

Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis

Literature references

^[1] B. Baumeister, et al. (2003) Biopolymers, 71, 339.

聯結

Replaces: 04-12-1279

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable