跳转至内容
Merck
所有图片(1)

Key Documents

更多文件

8.52089

Sigma-Aldrich

Fmoc-Dpr(Mtt)-OH

Novabiochem®

别名:

Fmoc-Dpr(Mtt)-OH, N-α-Fmoc-N-β-4-methyltrityl-L-diaminopropionic acid

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C38H34N2O4
CAS号:
654670-89-0
分子量:
582.69
分類程式碼代碼:
12352209
NACRES:
NA.22

品質等級

200

產品線

Novabiochem®

化驗

≥95% (TLC)
≥95.0% (HPLC)

形狀

powder

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商／商標名

Novabiochem®

應用

peptide synthesis

官能基

amine

儲存溫度

15-25°C

InChI

1S/C38H34N2O4/c1-26-20-22-29(23-21-26)38(27-12-4-2-5-13-27,28-14-6-3-7-15-28)39-24-35(36(41)42)40-37(43)44-25-34-32-18-10-8-16-30(32)31-17-9-11-19-33(31)34/h2-23,34-35,39H,24-25H2,1H3,(H,40,43)(H,41,42)/t35-/m0/s1

InChI 密鑰

WDZDBCVDBMWMAM-DHUJRADRSA-N

一般說明

The side-chain Mtt group can be selectively removed with 1% TFA in DCM [1,2,3] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [4], making this an excellent derivative for the synthesis of branched peptides and peptides modified at the Dpr side-chain [4,5], and for the construction of templates and multifunctionalized resins for combinatorial synthesis[6].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

[1] K. Barlos, et al., C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283.
[2] A. Aletras, et al. (1995) Int. J. Peptide Protein Res., 45, 488.
[3] L. Bourel, et al. (2000) J. Peptide Sci., 6, 264.
[4] K. Barlos, personal communication.
[5] P. Hoogerhout, et al. (1999) J. Peptide Res., 54, 436.
[6] C. Park & K. Burgess (2001) J. Comb. Chem., 3, 257.

聯結

Replaces: 04-12-1204

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): +10.0 - +13.0 °
Purity (TLC(157A)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

商品

Selecting Orthogonal Building Blocks

Novabiochem® product range has one of the largest collections of orthogonally and quasi-orthogonally protected tri-functional amino acids. These derivatives are useful tools for the synthesis of cyclic and branched peptides and peptides carrying side-chain modifications.

Selecting Orthogonal Building Blocks

Novabiochem® product range has one of the largest collections of orthogonally and quasi-orthogonally protected tri-functional amino acids. These derivatives are useful tools for the synthesis of cyclic and branched peptides and peptides carrying side-chain modifications.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门