5.32586

AEBSF, HCl ≥99% by HPLC

• 别名: AEBSF, HCl ≥99% by HPLC, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl
• 经验公式（希尔记法）: C₈H₁₀FNO₂S · xHCl
• CAS号: 30827-99-7
• 分子量: 203.23 (free base basis)
• MDL號碼: MFCD00132962
• 分類程式碼代碼: 12352200

属性

• 化驗: ≥99% (HPLC)
• 品質等級: 100
• 形狀: powder
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated; protect from light
• 顏色: white
• 溶解度: H₂O: 50 mg/mL
• 儲存溫度: 2-8°C
• InChI: 1S/C8H10FNO2S.ClH/c9-13(11,12)8-3-1-7(2-4-8)5-6-10;/h1-4H,5-6,10H2;1H
• InChI 密鑰: WRDABNWSWOHGMS-UHFFFAOYSA-N

说明

一般說明

AEBSF >99%; 30827-99-7

Specific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K. A material with ≥97% purity by HPLC (Cat. No. 101500) & its InSolution is also available (Cat. No. 508436).

Specific irreversible inhibitor of serine proteases. Reacts covalently with a serine at the active site. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). Used at the same molar concentration (0.1-1.0 mM) as PMSF for most applications. Exhibits low inhibitory activity towards proteinase K. A material with ≥97% purity by HPLC (Cat. No. 101500) & its InSolution is also available (Cat. No. 508436).

Please note that the molecular weight for this compound is batch-specific due to variable water content.

生化／生理作用

Primary Target
Serine proteases

Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Corrosive (L)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他說明

Citron, M., et al. 1996. Neuron17, 171.

Ohkubo, I., et al. 1994. J. Biochem.116, 1182.

Mintz, G.R. 1993. BioPharm.6, 34.

Lawson, W.B., et al. 1982. Folia Haematol.109, 52.

Markwardt, F., et al. 1974. Biochem. Pharmacol.23, 2247.
Markwardt, F., et al. 1973. Thromb. Res.2, 343.
Baker, B.R., and Cory, M. 1971. J. Med. Chem.14, 119.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS05
• 訊號詞: Danger
• 危險聲明: H314
• 防範說明: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• 危險分類: Eye Dam. 1 - Skin Corr. 1A
• 儲存類別代碼: 8A - Combustible, corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable