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Merck
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主要文件

481975

Sigma-Aldrich

(--)-Nicotine, Ditartrate

Potent agonist of the nicotinic acetylcholine receptor.

别名:

(--)-Nicotine, Ditartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di- d-tartrate, (S)-3-(1-Methyl-2-pyrrolindinyl)pyridine, Di-d-tartrate

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About This Item

经验公式(希尔记法):
C10H14N2 · 2C4H6O6
CAS号:
分子量:
462.41
分類程式碼代碼:
12352210
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

顏色

white to off-white

溶解度

ethanol: 10 mg/mL
water: 10 mg/mL

運輸包裝

ambient

儲存溫度

10-30°C

InChI

1S/C10H14N2.2C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;2*5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;2*1-2,5-6H,(H,7,8)(H,9,10)/t;2*1-,2-/m.11/s1

InChI 密鑰

RFEJUZJILGIRHQ-WBPXWQEISA-N

一般說明

Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.

生化/生理作用

Cell permeable: no
Primary Target
Nicotinic acetylcholine receptor
Product does not compete with ATP.
Reversible: no

警告

Toxicity: Highly Toxic (H)

重構

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 6 months at -20°C.

其他說明

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Rand, M.J. 1989. Prog. Brain Res. 79, 3.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

289.8 °F

閃點(°C)

143.2 °C


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Yan Wang et al.
Oncology reports, 40(4), 2097-2104 (2018-07-18)
Store‑operated calcium entry (SOCE) is critical for regulating the proliferation and metastasis of various cancer types. The present study aimed to investigate the role of SOCE on nicotine‑promoted proliferation of non‑small cell lung cancer (NSCLC) A549 cells. Cell proliferation was

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