444234

MMP-9-Lipocalin-TIMP-1 Complex, Human Neutrophil

• 别名: Matrix Metalloproteinase 9-Lipocalin-TIMP-1 Complex
• 分類程式碼代碼: 12352202
• NACRES: NA.77

属性

• 化驗: ≥90% (SDS-PAGE)
• 品質等級: 100
• 形狀: liquid
• 比活性: ≥600 mU/mg protein
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; avoid repeated freeze/thaw cycles
• 異物活動: other MMP activity, none detected
• 運輸包裝: wet ice
• 儲存溫度: −70°C

说明

一般說明

Native MMP-9-Lipocalin-TIMP-1 complex from stimulated human neutrophils. The ternary MMP-9/lipocalin/TIMP-1 complex behaves like the Pro-MMP-9/TIMP-1 complex, acting as an inhibitor of active MMPs. Following activation, the complex acts as a gelatinase, with reduced activity.

Native MMP-9-Lipocalin-TIMP-1 complex from stimulated human neutrophils. The ternary MMP-9/lipocalin/TIMP-1 complex behaves like the progelatinase B/TIMP-1 complex in acting as an inhibitor of active MMPs. Following activation, the complex acts as a gelatinase with reduced activity.

Note: 1 mU = 1 milliunit.

警告

Toxicity: Standard Handling (A)

單位定義

One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol 2,4-DNP-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH per min at 37°C, pH 7.0.

外觀

In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ^® 35 Detergent, 0.05% NaN₃, pH 7.0.

準備報告

Prepared from stimulated neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

重構

Following initial thaw, aliquot and freeze (-70°C).

其他說明

Kolkenbrock, H., et al. 1996. Biol. Chem. 377, 529.

法律資訊

Brij is a registered trademark of Croda International PLC

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable