推荐产品
化驗
≥98% (SDS-PAGE)
品質等級
形狀
lyophilized
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
desiccated
運輸包裝
wet ice
儲存溫度
−20°C
一般說明
Recombinant, human interferon-β (IFN-β) expressed in CHO cells as a single glycosylated polypeptide containing 166 amino acids. Purified by chromatographic methods. IFN-β is a type I cytokine produced in response to exposure to viruses or double-stranded RNAs. It is also induced by other cytokines, such as TNF and IL-1. It is involved in the regulation of non-specific humoral immune responses and immune responses to viral infections, and thus exhibits anti-viral, anti-proliferative, and immunomodulating properties. The biological activity of IFN-β, unlike IFN-α, is strictly species-specific and will not be active across species.
Recombinant, human interferon-β (IFN-β) expressed in CHO cells as a single glycosylated polypeptide containing 166 amino acids. Purified by chromatographic methods. IFN-β is a type I cytokine produced in response to exposure to viruses or double-stranded RNAs. It is also induced by other cytokines, such as TNF and IL-1. It is involved in the regulation of non-specific humoral immune responses and immune responses to viral infections, and thus exhibits anti-viral, anti-proliferative, and immunomodulating properties. The biological activity of IFN-β, unlike IFN-α, is strictly species-specific and will not be active across species.
生化/生理作用
Reported as IU/mg on a lot-specific basis using a viral resistance assay
警告
Toxicity: Standard Handling (A)
外觀
Lyophilized from 62 mg/ml mannitol, 9.1 mg/ml human albumin, 0.9 mg/ml acetate, pH 7.0-7.2.
重構
Following reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 7 days at 4°C or for up to 4 months at -20°C. Avoid freeze/thaw cycles of solutions.
Reconstitute with sterile water to ≥100 µg/ml, containing 0.1% HSA or BSA. Further dilute with aqueous buffer just prior to use.
其他說明
Goebel, M.U., et al. 2005. Physiol. Behav.84, 807.
Graber, J., et al. 2005. J. Neuroimmunol.161,169.
Mallada-Frechin, J., et al. 2005. Rev. Neurol.40, 482.
Patten, S.B., et al. 2005. Mult. Scler.11, 175.
Pohl, D., et al. 2005. Neurology64, 888.
Schwid, S.R., et al. 2005. Arch. Neurol.62, 785.
Graber, J., et al. 2005. J. Neuroimmunol.161,169.
Mallada-Frechin, J., et al. 2005. Rev. Neurol.40, 482.
Patten, S.B., et al. 2005. Mult. Scler.11, 175.
Pohl, D., et al. 2005. Neurology64, 888.
Schwid, S.R., et al. 2005. Arch. Neurol.62, 785.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
Journal of virology, 96(7), e0004922-e0004922 (2022-03-24)
Heartland bandavirus (HRTV), which is an emerging tick-borne virus first identified in Missouri in 2009, causes fever, fatigue, decreased appetite, headache, nausea, diarrhea, and muscle or joint pain in humans. HRTV is genetically close to Dabie bandavirus, which is the
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