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Key Documents

33-016

Sigma-Aldrich

PI3-激酶 HTRF ®含量测定;384 孔

The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

别名:

Assay for PI 3-Kinase, HTRF Assay, PI 3-Kinase Assay

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質等級

物種活性

human, mouse

製造商/商標名

HTRF®
Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

UniProt登錄號

檢測方法

fluorometric (HTRF)

運輸包裝

dry ice

基因資訊

human ... PIK3CA(5290)

應用

用于检测/量化:PI 3-激酶

生化/生理作用

靶标亚家族:PI3K/PI4K

包裝

试剂盒容量:384孔

成分

4X反应缓冲液

PIP2(底物;1mM储备液)

终止试剂A

终止试剂B

DM A检测试剂

DM B检测试剂

DM C检测试剂

法律資訊

HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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James M J Dickson et al.
Bioscience reports, 33(6) (2013-08-24)
NTT (N-terminal tags) on the catalytic (p110) sub-unit of PI 3-K (phosphoinositol 3-kinase) have previously been shown to increase cell signalling and oncogenic transformation. Here we test the impact of an NT (N-terminal) His-tag on in vitro lipid and protein
Stephen Jamieson et al.
The Biochemical journal, 438(1), 53-62 (2011-06-15)
Genetic alterations in PI3K (phosphoinositide 3-kinase) signalling are common in cancer and include deletions in PTEN (phosphatase and tensin homologue deleted on chromosome 10), amplifications of PIK3CA and mutations in two distinct regions of the PIK3CA gene. This suggests drugs
Christina M Buchanan et al.
PloS one, 8(8), e71337-e71337 (2013-08-13)
In addition to lipid kinase activity, the class-I PI 3-kinases also function as protein kinases targeting regulatory autophosphorylation sites and exogenous substrates. The latter include a recently identified regulatory phosphorylation of the GM-CSF/IL-3 βc receptor contributing to survival of acute
Qin Li et al.
Toxicology research, 8(3), 353-360 (2019-06-05)
Qingkailing injection (QKLI) is a kind of multi-component traditional Chinese medicine injection. It has been widely used in clinical practice, but in recent years, it has caused more and more adverse reactions, mainly manifested as pseudo-allergic symptoms. To explore the

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