218773

Caspase-8 Inhibitor I, Cell-Permeable

The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.

• 别名: Caspase-8 Inhibitor I, Cell-Permeable, Granzyme B Inhibitor II, Cell-permeable, IETD-CHO, Cell-permeable
• 经验公式（希尔记法）: C₉₅H₁₆₂N₂₀O₂₆
• 分子量: 2000.42
• 分類程式碼代碼: 12352200

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: lyophilized solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: DMSO: 5 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A potent, cell-permeable, and reversible inhibitor of caspase-8 and Granzyme B. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.

Potent, cell-permeable and reversible inhibitor of caspase-8 and Granzyme B.

生化／生理作用

Cell permeable: yes

Primary Target
caspase-8

Product does not compete with ATP.

Reversible: yes

警告

Toxicity: Standard Handling (A)

序列

Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Hamada, E., et al. 1990. J. Hepatol. 30, 807.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable