210150

Cantharidic Acid

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

• 别名: Cantharidic Acid, 5ʹ-3ʹ2,3-Dicarboxy-2,3-dimethyl-1,4-epoxycyclohexane, exo-1,6-Dicarboxy- endo-1,6-dimethyl-7-oxabicylco[2,2,1]heptane
• 经验公式（希尔记法）: C₁₀H₁₄O₅
• CAS号: 28874-45-5
• 分子量: 214.22
• MDL號碼: MFCD00047137
• 分類程式碼代碼: 12352106
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: >95% (TLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 溶解度: warm ethanol: 10 mg/mL; DMSO: 25 mg/mL
• 運輸包裝: ambient
• 儲存溫度: 10-30°C
• InChI: 1S/C10H14O5/c1-9(7(11)12)5-3-4-6(15-5)10(9,2)8(13)14/h5-6H,3-4H2,1-2H3,(H,11,12)(H,13,14)/t5-,6+,9-,10+
• InChI 密鑰: NMTNUQBORQILRK-YUMGAWCOSA-N

说明

一般說明

A potent inhibitor of protein phosphatase 2A (IC₅₀ = 50 nM).

Inhibits protein phosphatase 2A (IC₅₀ = 50 nM).

生化／生理作用

Cell permeable: no

Primary Target
PP2A

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 50 nM against protein phosphatase 2A

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliqot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Zhang, Z., et al. 1996. Biochemistry35, 1606.
Li, Y.-M., and Casida, J.E. 1992. Proc. Natl. Acad. Sci. USA89, 11867.
Graziano, M.J., et al. 1988. Mol. Pharmacol.33, 706.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3