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Key Documents

178479

Sigma-Aldrich

抗载脂蛋白E山羊pAb

liquid, Calbiochem®

别名:

Anti-ApoE antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

goat

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

liquid

包含

≤0.1% sodium azide as preservative

物種活性

human, rat, mouse

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
avoid repeated freeze/thaw cycles

同型

IgG

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

一般說明

山羊多克隆抗体作为血清提供,已在Tris-HCl缓冲液中进行了去纤维蛋白,脱脂和透析。识别载脂蛋白E蛋白。
抗载脂蛋白E,山羊多克隆,识别人载脂蛋白E。不与其他载脂蛋白交叉反应。它已通过ELISA,免疫沉淀和自由浮动切片的验证。
识别人载脂蛋白E。不与其他载脂蛋白交叉反应。
  • 抗体靶基因符号:APOE
  • 靶标异名:AD2, AI255918, APOE2, APOE4, APOEA, 载脂蛋白E, LDLCQ5, LPG, MGC1571
  • 输入基因名称:载脂蛋白E
  • Hu Entrez ID:348(相关抗体:NE1004
  • Mu Entrez ID:11816
  • 大鼠Entrez ID:25728
  • 免疫原

    纯化重组人载脂蛋白E

    應用

    ELISA(1:8000)

    免疫沉淀(请参阅注释)

    自由浮动切片(请参阅应用参考)

    包裝

    请参考特定浓度批号的标签。

    警告

    毒性:标准处理(A)

    外觀

    在500 mM NaCl,50 mM Tris-HCl(pH 7.5)中。

    重構

    初次融化后,等分并冷冻(-20°C)。

    其他說明

    通过免疫电泳(IEP)对两次浓缩的合并人血清测定的单特异性。据报道,该抗体也可与免疫沉淀作用。合适的工作稀释度由与测定条件相关的变量决定。

    法律資訊

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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    儲存類別代碼

    10 - Combustible liquids

    水污染物質分類(WGK)

    WGK 1

    閃點(°F)

    Not applicable

    閃點(°C)

    Not applicable


    分析证书(COA)

    输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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    Emilie L Castranio et al.
    Neurobiology of disease, 105, 1-14 (2017-05-16)
    Traumatic brain injury (TBI) is strongly linked to an increased risk of developing dementia, including chronic traumatic encephalopathy and possibly Alzheimer's disease (AD). APOEε4 allele of human Apolipoprotein E (APOE) gene is the major genetic risk factor for late onset
    Suzanne E Wahrle et al.
    The Journal of biological chemistry, 279(39), 40987-40993 (2004-07-23)
    ABCA1 is an ATP-binding cassette protein that transports cellular cholesterol and phospholipids onto high density lipoproteins (HDL) in plasma. Lack of ABCA1 in humans and mice causes abnormal lipidation and increased catabolism of HDL, resulting in very low plasma apoA-I
    Michael Landowski et al.
    Proceedings of the National Academy of Sciences of the United States of America, 116(9), 3703-3711 (2019-02-28)
    One of the strongest susceptibility genes for age-related macular degeneration (AMD) is complement factor H (CFH); however, its impact on AMD pathobiology remains unresolved. Here, the effect of the principal AMD-risk-associated CFH variant (Y402H) on the development and progression of
    Ema Ozaki et al.
    Experimental eye research, 217, 108953-108953 (2022-01-30)
    As the resident immune cells in the retina, microglia play important homeostatic roles in retinal immune regulation and neuroprotection. However, chronic microglia activation is a common hallmark of many degenerative retinal diseases. The semi-synthetic tetracycline antibiotic, minocycline, appears to inhibit
    Shan-May Yong et al.
    Scientific reports, 4, 6580-6580 (2014-10-11)
    The effect of ApoE on NMDAR-dependent ERK/CREB signaling is isoform-dependent, and ApoE4 accelerates memory decline in ageing. However, this isoform-dependent function on neuronal signaling during ageing is unclear. In this study, we have examined NMDAR-associated ERK/CREB signal transduction in young

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