生物源
mouse
品質等級
共軛
ALEXA FLUOR™ 555
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
1A6, monoclonal
物種活性
vertebrates
製造商／商標名
Upstate®
技術
flow cytometry: suitable
western blot: suitable
同型
IgG2bκ
運輸包裝
wet ice
目標翻譯後修改
nitration (Tyr)
基因資訊
human ... NOS1(4842)
特異性
recognizes nitrated protein
免疫原
Nitrated KLH
應用
Anti-Nitrotyrosine Antibody, clone 1A6, Alexa Fluor 555 conjugate is an antibody against Nitrotyrosine for use in FC & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Oxidative Stress
Oxidative Stress
品質
Routinely evaluated by immunoblot.
標靶描述
The molecular weight is related to the nitrated protein
外觀
Protein G Purified
儲存和穩定性
1 year at 4°C from date of shipment
法律資訊
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Alexa Fluor is a registered trademark of Molecular Probes, Inc.
Alexa Fluor is a registered trademark of Molecular Probes, Inc.
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儲存類別代碼
10 - Combustible liquids
Biological significance of nitric oxide-mediated protein modifications.
Gow, Andrew J, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 287, L262-L268 (2004)
Ming-Hui Zou et al.
The Journal of clinical investigation, 109(6), 817-826 (2002-03-20)
Nitric oxide (NO) is produced by NO synthase (NOS) in many cells and plays important roles in the neuronal, muscular, cardiovascular, and immune systems. In various disease conditions, all three types of NOS (neuronal, inducible, and endothelial) are reported to
Zarema Balafanova et al.
The Journal of biological chemistry, 277(17), 15021-15027 (2002-02-13)
Activation of protein kinase C (PKC) epsilon by nitric oxide (NO) has been implicated in the development of cardioprotection. However, the cellular mechanisms underlying the activation of PKCepsilon by NO remain largely unknown. Nitration of protein tyrosine residues has been
J Torreilles et al.
BMC immunology, 2, 1-1 (2001-03-07)
Peroxynitrite is increasingly proposed as a contributor to defence system in marine bivalve. It can be formed by combination of superoxide and nitric oxide, and can react with tyrosine residues of proteins giving rise to 3-nitrotyrosine. The present article describes
C Ayata et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(18), 6908-6917 (1997-09-15)
We investigated the role of neuronal (type I) nitric oxide synthase (nNOS) in NMDA-mediated excitotoxicity in wild-type (SV129 and C57BL/6J) and type I NOS knock-out (nNOS-/-) mice and examined its relationship to apoptosis. Excitotoxic lesions were produced by intrastriatal stereotactic
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