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Merck
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Key Documents

1.50974

Supelco

Superspher® 60 RP-select B (4 µm) HPLC Columns

L x I.D. 75 mm x 4 mm, LiChroCART HPLC cartridge, manuCART holder required for use

别名:

TM=["Superspher"] C8 TM=["LICHROCART"] cartridge for HPLC

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About This Item

分類程式碼代碼:
41115709
NACRES:
SB.52

product name

Superspher® 60 RP-select B LiChroCART 75-4, suitable for HPLC

材料

stainless steel column

品質等級

agency

suitable for USP L7

產品線

Superspher®

特點

endcapped: no

參數

250 bar pressure
60 °C max. temp.

技術

HPLC: suitable
mass spectrometry (MS): suitable (Low - Medium)

柱長度 × 內徑

7.5 cm × 4 mm

基質

fully porous particle

基質活性組

C8 bonding phase

粒徑

4 μm

孔徑

60 Å pore size

工作pH值範圍

2-7.5

分離技術

reversed phase

儲存溫度

no temp limit

一般說明

HPLC柱
Superspher® RP-select B是一种高度可重复性经传统生产的球形硅胶载体,具有反相特性和C-8相的疏水性。这个载体非常适合于碱性化合物的分离,但在中性和酸性化合物的测定中也有较好的性能。粒径为4µm的高性能二氧化硅载体可获得出色的压力/分离性能比。这种吸附剂被装入LiChroCART 75-4 HPLC柱中。HPLC系统的连接是通过使用 manu-CART NT柱支架(1.51486)完成的。

應用


  • Screening, library-assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma: This study demonstrates the application of liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization for the screening and quantification of various compounds in plasma, utilizing the high-resolution capabilities of the Superspher 60 RP-select B column (Kratzsch et al., 2004).

  • Screening, library-assisted identification and validated quantification of fifteen neuroleptics and three of their metabolites in plasma: Employing liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization, this study utilized the Superspher 60 RP-select B to detect and quantify neuroleptics in plasma, showcasing its utility in pharmaceutical and clinical research (Kratzsch et al., 2003).

  • Validated assay for quantification of oxcarbazepine and its active dihydro metabolite 10-hydroxycarbazepine in plasma: This research highlights the column′s application in therapeutic drug monitoring using atmospheric pressure chemical ionization liquid chromatography/mass spectrometry, reflecting its precision and reliability in clinical pharmacology (Maurer et al., 2002).

分析報告

压力: ≤ 50 bar
理论板数(N/m)(1,2-苯并蒽): ≥ 85000
对称性(1,2-苯并蒽):0.8 - 1.4
容量系数(1,2-苯并蒽): ≥ 2.5

法律資訊

LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany
Superspher is a registered trademark of Merck KGaA, Darmstadt, Germany

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