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Merck
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Key Documents

14-623-M

Sigma-Aldrich

HIPK2 Protein, active, 10 µg

Active, N-terminal His6-tagged, recombinant, human HIPK2, amino acids 165-564, for use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

human

品質等級

100
300

重組細胞

expressed in baculovirus infected Sf21 cells

分子量

Mw 49.6 kDa

製造商／商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

NM_022740.2

UniProt登錄號

Q9H2X6

基因資訊

human ... HIPK2(28996)

一般說明

N-terminal His6-tagged, recombinant, human HIPK2, amino acids 165-564
Product Source: baculovirus in Sf21 insect cells

應用

Research Category
Inflammation & Immunology

生化／生理作用

Protein Target: HIPK2
Target Sub-Family: CMGC

品質

routinely evaluated by phosphorylation of 0.33mg/ml MBP (Catalog # 13-104)

外觀

Ni2+/NTA-agarose

儲存和穩定性

6 months at -70°C

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H317

危險分類

Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Jae J Song et al.
The Journal of biological chemistry, 278(47), 47245-47252 (2003-09-12)
Overexpression of JNK binding domain inhibited glucose deprivation-induced JNK1 activation, relocalization of Daxx from the nucleus to the cytoplasm, and apoptosis signal-regulating kinase 1 (ASK1) oligomerization in human prostate adenocarcinoma DU-145 cells. However, SB203580, a p38 inhibitor, did not prevent
Y H Kim et al.
The Journal of biological chemistry, 273(40), 25875-25879 (1998-09-25)
A novel family of cofactors that differentially interact with homeoproteins have been identified via a yeast two-hybrid screen. The proteins contain a conserved protein kinase domain that is separated from a domain that interacts with homeoproteins and hence are termed
Jeffrey A Ecsedy et al.
Molecular and cellular biology, 23(3), 950-960 (2003-01-17)
We describe an interaction between homeodomain-interacting protein kinase 1 (HIPK1) and Daxx, two transcriptional regulators important in transducing growth-regulatory signals. We demonstrate that HIPK1 is ubiquitously expressed in mice and humans and localizes predominantly to the nucleus. Daxx normally resides

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