生物源
human
品質等級
重組細胞
expressed in Sf21 cells
分子量
Mw 49.2 kDa
製造商/商標名
Upstate®
技術
activity assay: suitable (kinase)
UniProt登錄號
運輸包裝
dry ice
基因資訊
human ... MAPK9(5601)
一般說明
N-terminal His6-tagged, recombinant, full-length, human JNK2α2/SAPK1a unactive
Product Source: Expressed in Sf21 insect cells
生化/生理作用
Protein Target: JNK2α2/SAPK1a
Target Sub-Family: CMGC
品質
Routinely evaluated by phosphorylation of JNK2α2/SAPK1a
外觀
Ni2+/NTA-agarose
儲存和穩定性
1 year at -20°C
其他說明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
The EMBO journal, 15(11), 2760-2770 (1996-06-03)
The JNK protein kinase is a member of the MAP kinase group that is activated in response to dual phosphorylation on threonine and tyrosine. Ten JNK isoforms were identified in human brain by molecular cloning. These protein kinases correspond to
Science (New York, N.Y.), 267(5196), 389-393 (1995-01-20)
Treatment of cells with pro-inflammatory cytokines or ultraviolet radiation causes activation of the c-Jun NH2-terminal protein kinase (JNK). Activating transcription factor-2 (ATF2) was found to be a target of the JNK signal transduction pathway. ATF2 was phosphorylated by JNK on
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