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Merck
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Key Documents

14-330

Sigma-Aldrich

JNK2α2/SAPK1a Protein, inactive, 50 g

Unactive, N-terminal His6-tagged, recombinant, full-length, human JNK2α2/SAPK1a unactive, for use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

human

品質等級

重組細胞

expressed in Sf21 cells

分子量

Mw 49.2 kDa

製造商/商標名

Upstate®

技術

activity assay: suitable (kinase)

UniProt登錄號

運輸包裝

dry ice

基因資訊

human ... MAPK9(5601)

一般說明

N-terminal His6-tagged, recombinant, full-length, human JNK2α2/SAPK1a unactive
Product Source: Expressed in Sf21 insect cells

生化/生理作用

Protein Target: JNK2α2/SAPK1a
Target Sub-Family: CMGC

品質

Routinely evaluated by phosphorylation of JNK2α2/SAPK1a

外觀

Ni2+/NTA-agarose

儲存和穩定性

1 year at -20°C

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2


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S Gupta et al.
The EMBO journal, 15(11), 2760-2770 (1996-06-03)
The JNK protein kinase is a member of the MAP kinase group that is activated in response to dual phosphorylation on threonine and tyrosine. Ten JNK isoforms were identified in human brain by molecular cloning. These protein kinases correspond to
S Gupta et al.
Science (New York, N.Y.), 267(5196), 389-393 (1995-01-20)
Treatment of cells with pro-inflammatory cytokines or ultraviolet radiation causes activation of the c-Jun NH2-terminal protein kinase (JNK). Activating transcription factor-2 (ATF2) was found to be a target of the JNK signal transduction pathway. ATF2 was phosphorylated by JNK on

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