12-523

GST, 6 His-tagged

• 分類程式碼代碼: 12352204
• eCl@ss: 32160405
• NACRES: NA.41

属性

• 形狀: liquid
• 品質等級: 100
• 製造商／商標名: Upstate^®
• 技術: affinity chromatography: suitable
• NCBI登錄號: NM_000852.2
• UniProt登錄號: P09211
• 運輸包裝: dry ice

说明

一般說明

Glutathione S-transferase (GST) belongs to three families of proteins distinguished as cytosolic, mitochondrial, and microsomal GST. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: α, κ, μ, ω, π, σ, θ, and ζ. This product is a C-terminal 6 histidine-tagged, recombinant full-length glutathione S-transferase (GST).

生化／生理作用

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in phase II detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

外觀

50mM Tris-HCl, pH 8, 150mM NaCl, 20% glycerol

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2