1.06757

4-羟基苯甲酸甲酯

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, NF

• 别名: Methyl 4-hydroxybenzoate, Methylparaben, 4-Hydroxybenzoic acid methyl ester
• 线性分子式: 4-(OH)C₆H₄(COOCH₃)
• CAS号: 99-76-3
• 分子量: 152.15
• MDL號碼: MFCD00002352
• 分類程式碼代碼: 12352108
• 酶委員會索引編號: 202-785-7

属性

• agency: BP; ChP; JP; NF; Ph. Eur.
• 品質等級: 500
• 蒸汽壓力: 0.000005 hPa ( 20 °C)
• 產品線: EMPROVE^® EXPERT
• 化驗: 99.0-100.5% (HPLC); 99.0-102.0% (acidimetric)
• 形狀: solid
• 自燃溫度: >600 °C
• 技術: API processing | cocrystal formation: suitable
• pH值: 5.8 (20 °C in H₂O, saturated solution)
• mp: 125 °C
• 溶解度: 1.88 g/L
• 密度: 1.38 g/cm³ at 20 °C
• 應用: liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation; solid formulation
• 儲存溫度: 15-25°C
• SMILES 字串: O(C)C(=O)c1ccc(cc1)O
• InChI: 1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
• InChI 密鑰: LXCFILQKKLGQFO-UHFFFAOYSA-N

说明

一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Methyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like propyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

安全信息

• 象形圖: GHS09
• 危險聲明: H411
• 防範說明: P273 - P391 - P501
• 危險分類: Aquatic Chronic 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 334.4 °F
• 閃點（°C）: 168 °C