1.01005

1,1,1-三氯-2-甲基-2-丙醇半水合物

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF

• 别名: 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate, Acetone chloroform, Chlorbutol, Chloretone, Chlorobutanol
• 经验公式（希尔记法）: C₄H₇Cl₃O · 0.5H₂O
• CAS号: 6001-64-5
• 分子量: 186.46
• MDL號碼: MFCD02179352
• 分類程式碼代碼: 12352104
• 酶委員會索引編號: 200-317-6

属性

• agency: BP; JP; NF; Ph. Eur.
• 品質等級: 500
• 產品線: EMPROVE^® ESSENTIAL
• 形狀: solid
• pH值: 4.5-6 (20 °C, 7.7 g/L in H₂O)
• bp: 167 °C/1013 hPa
• mp: 78 °C
• 轉變溫度: flash point 100 °C
• 溶解度: 7.7 g/L
• 應用: liquid formulation; ophthalmics; pharmaceutical
• 儲存溫度: 15-25°C
• InChI: 1S/2C4H7Cl3O.H2O/c2*1-3(2,8)4(5,6)7;/h2*8H,1-2H3;1H2
• InChI 密鑰: WRWLCXJYIMRJIN-UHFFFAOYSA-N

说明

一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) is typically used as a preservative in pharmaceutical formulations. It has antimicrobial properties and is active against bacteria and fungi.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

The substance 1.01005 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 212.0 °F - closed cup
• 閃點（°C）: 100 °C - closed cup