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Merck
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主要文件

07-787

Sigma-Aldrich

Anti-phospho-Abl (Tyr245) Antibody

Upstate®, from rabbit

别名:

ABL1, JTK7, c-ABL, p150, v-abl

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human, mouse, rat

製造商/商標名

Upstate®

技術

ELISA: suitable
western blot: suitable

同型

IgG

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

phosphorylation (pTyr245)

基因資訊

human ... ABI1(10006)
mouse ... Abi1(11308)
rat ... Abi1(79249)

特異性

Other species have not been tested.
Recognizes both Abl and BCR-Abl when phosphorylated on tyrosine residue corresponding to Tyr245 in Abl.

免疫原

KLH-conjugated peptide corresponding to amino acid region encompassing human c-Abl Tyr245.

應用

Anti-phospho-Abl (Tyr245) Antibody is an antibody against phospho-Abl (Tyr245) for use in ELISA & WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

General Post-translation Modification

品質

Routinely evaluated by immunoblot.

標靶描述

145 kDa (210 kDa for BCR-Abl)

外觀

ImmunoAffinity Purified

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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A common phosphotyrosine signature for the Bcr-Abl kinase
Goss, Valerie L, et al
Blood, 107, 4888-4897 (2006)
Phosphoproteomic analysis of AML cell lines identifies leukemic oncogenes
Walters, Denise K, et al
Leukemia Research, 30, 1097-1104 (2006)
Phosphotyrosine mapping in Bcr/Abl oncoprotein using phosphotyrosine-specific immonium ion scanning
Steen, Hanno, et al
Molecular and Cellular Proteomics, 2, 138-145 (2003)
Anna Stenqvist et al.
Neuroscience letters, 435(1), 11-16 (2008-03-21)
Ret is a receptor tyrosine kinase for the GDNF family of ligands and plays important roles during nervous system development for cell proliferation, cell migration and neurite growth. Signaling initiated from intracellular tyrosine 1062, by recruitment of several different phosphotyrosine

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