跳转至内容
Merck
所有图片(1)

主要文件

07-758

Sigma-Aldrich

抗磷-Flt-1 (Tyr1213)抗体

Upstate®, from rabbit

别名:

Vascular endothelial growth factor receptor 1 (VEGFR-1), Vascular permeability factor receptor, Tyrosine-protein kinase FRT, Fms-like tyrosine kinase

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

bovine, human, goat, sheep, rat, mouse

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

phosphorylation (pTyr1213)

基因資訊

bovine ... Flt1(503620)
human ... FLT1(2321)
mouse ... Flt1(14254)
rat ... Flt1(54251)

特異性

识别磷酸-Flt-1 (Tyr1213)。

免疫原

KLH缀合的合成肽,包含序列(...VR[pY]VN...),其中[pY]对应于人Flt-1残基1213处的磷酸酪氨酸。免疫序列在狨猴中相同,在大鼠、山羊、绵羊、奶牛和恒河猴中有14/15个相同氨基酸,在小鼠中有13/15个相同氨基酸。

應用

抗磷酸-Flt-1 (Tyr1213)抗体可检测磷酸-Flt-1 (Tyr1213)水平 & 已发布 & 经验证可用于WB。
研究子范畴
生长因子 & 受体
研究类别
信号传导

品質

通过免疫印迹法对ATP孵育后磷酸化的重组Flt-1(目录号14-562)进行常规评估

標靶描述

~180 kDa(QC检测片段为66 kDa)

外觀

免疫亲和性纯化兔IgG ,溶于0.1 Tris-甘氨酸(pH 7.4)、0.15 NaCl和0.05%叠氮化钠中。
免疫亲和纯化

儲存和穩定性

自收到之日起,在2-8°C条件下可稳定保存1年。 避免反复冻融循环,以免损坏IgG和影响产品性能。

分析報告

对照
重组Flt-1(目录号14-562)被ATP磷酸化

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

未找到合适的产品?  

试试我们的产品选型工具.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Paul Mésange et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 24(11), 2548-2558 (2018-03-02)
Purpose: There is extensive cross-talk between VEGF- and EGFR-pathway signaling in colorectal cancer. However, combinations of VEGF- and EGFR-targeted monoclonal antibodies (mAb) show disappointing activity, in particular for patients with mutant RAS Previous results show that tyrosine kinase inhibitors (TKI)
EGFR- and VEGF(R)-targeted small molecules show synergistic activity in colorectal cancer models refractory to combinations of monoclonal antibodies.
Poindessous, V; Ouaret, D; El Ouadrani, K; Battistella, A; Megalophonos, VF; Kamsu-Kom et al.
Clinical cancer research : an official journal of the American Association for Cancer Research null
Zheng Zhou et al.
American journal of cancer research, 5(10), 3149-3161 (2015-12-23)
Angiogenesis is central to the growth of cancers and VEGFR-1/Flt-1 plays an important role during the neovascularization under pathological conditions. We previously founded a VEGFR1 antagonistic peptide, F56, by screening the phage peptide library. We showed that DHFR-F56 chimeric protein
Chuanke Zhao et al.
Cancer science, 106(11), 1596-1606 (2015-08-25)
Angiogenesis is a prerequisite of tumor growth and metastasis and, thus, anti-angiogenesis treatment has become an important part of cancer therapy. A 15-amino acid peptide of the fibrinogen α chain, fibrinostatin, was previously found in serum samples of gastric cancer
Weihua Guan et al.
PloS one, 6(9), e24551-e24551 (2011-09-14)
We identified that the angiotensin receptor antagonist, candesartan, has profound neurovascular protective properties when administered after ischemic stroke and was associated with a proangiogenic state at least partly explained by vascular endothelial growth factor A (VEGFA). However, the spatial distribution

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门