生物源
rabbit
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
mouse, human, rat
製造商／商標名
Upstate®
技術
western blot: suitable
同型
IgG
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... HDAC5(10014)
特異性
HDAC5
免疫原
KLH-conjugated synthetic peptides corresponding to amino acids 536-545 and 194-206 (C-TKTGELPRQP and C-KSKEPTPGGLNHS) of human HDAC5
應用
Detect HDAC5 also known as histone deacetylase 5 with Anti-HDAC5 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Weaker staining noticed in mouse and rat versus human.
品質
routinely evaluated by immunoblot on HeLa nuclear extract or HeLa whole cell lysate
標靶描述
160 kDa
外觀
Protein A chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl and 0.05% sodium azide.
Format: Purified
儲存和穩定性
Stable for 1 year at 2-8°C from date of receipt.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
Proteomic analyses of intermediate filaments reveals cytokeratin8 is highly acetylated--implications for colorectal epithelial homeostasis.
Sian H Leech,Caroline A Evans,Leila Shaw,Chi H Wong,Joanne Connolly,John R Griffiths et al.
Proteomics null
Hongbo Ling et al.
Cell cycle (Georgetown, Tex.), 11(20), 3779-3791 (2012-10-02)
Centrosome duplication is controlled both negatively and positively by a number of proteins. The activities and stabilities of those regulatory proteins are in many cases controlled by posttranslational modifications. Although acetylation and deacetylation are highly common posttranslational modifications, their roles
Lauren E Kernochan et al.
Human molecular genetics, 14(9), 1171-1182 (2005-03-18)
Increasing survival motor neuron 2 (SMN2) gene expression may be an effective strategy for the treatment of spinal muscular atrophy (SMA). Histone deacetylase (HDAC) inhibitors have been shown to increase SMN transcript and protein levels, but the specific role of
Oliver H Krämer et al.
The EMBO journal, 22(13), 3411-3420 (2003-07-04)
Histone-modifying enzymes play essential roles in physiological and aberrant gene regulation. Since histone deacetylases (HDACs) are promising targets of cancer therapy, it is important to understand the mechanisms of HDAC regulation. Selective modulators of HDAC isoenzymes could serve as efficient
Syed A H Zaidi et al.
Investigative ophthalmology & visual science, 61(11), 17-17 (2020-09-12)
We determined whether δ-opioid receptor agonist (SNC-121) regulates acetylation homeostasis via controlling histone deacetylases (HDACs) activity and expression in optic nerve head (ONH) astrocytes. ONH astrocytes were treated with SNC-121 (1 µM) for 24 hours. The HDAC activity was measured
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