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Merck
所有图片(1)

主要文件

06-236

Sigma-Aldrich

Giα1/2抗体

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, human, rat, bovine

製造商/商標名

Upstate®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... GNAI1(2770)

特異性

可识别Giα1和Giα2。

免疫原

10个残基的合成肽(KNNLKDCGLF),对应于Gia1和Gia2的C端

應用

可使用这种经验证可用于IC、IP & WB的Giα1/2抗体检测Giα1/2。
研究子类别
GPCR, cAMP/cGMP & 钙信号传导
研究类别
信号传导

品質

通过免疫印迹法对大鼠脑微粒体制备物或小鼠3T3/A31成纤维细胞的溶解质膜进行了常规评估

標靶描述

40 kDa

外觀

PBS(50 mM KHPO4、140 mM NaCl)稀释的兔血清。冷冻溶液
形式:纯化

儲存和穩定性

自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始小瓶进行离心。

分析報告

对照
广泛表达

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析证书(COA)

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J M Sands et al.
The Journal of clinical investigation, 99(6), 1399-1405 (1997-03-15)
During antidiuresis, increases in vasopressin (AVP)-elicited osmotic water permeability in the terminal inner medullary collecting duct (tIMCD) raise luminal calcium concentrations to levels (> or = 5 mM) above those associated with the formation of calcium-containing precipitates in the urine.
Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro
Ward, D. T., et al
The Journal of Biological Chemistry, 273, 14476-14483 (1998)
P Barrett et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14(11), 1619-1628 (2000-08-06)
Mimicking short photoperiod melatonin signals (16 h exposure) on primary cell cultures of melatonin target cells of the ovine pars tuberalis (PT) results in an enhanced cAMP response to forskolin stimulation relative to untreated cells, a phenomenon termed sensitization. The
Jian Shi et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(2), 702-715 (2015-10-16)
Depletion of sarcoplasmic reticulum (SR) Ca(2+) stores activates store-operated channels (SOCs) composed of canonical transient receptor potential (TRPC) 1 proteins in vascular smooth muscle cells (VSMCs), which contribute to important cellular functions. We have previously shown that PKC is obligatory
Rachna Kaushik et al.
Molecular biology of the cell, 14(8), 3144-3155 (2003-08-20)
Mammalian LGN/AGS3 proteins and their Drosophila Pins orthologue are cytoplasmic regulators of G-protein signaling. In Drosophila, Pins localizes to the lateral cortex of polarized epithelial cells and to the apical cortex of neuroblasts where it plays important roles in their

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