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BQ-788, Sodium Salt

• 别名: BQ-788, Sodium Salt, N- cis-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na
• 经验公式（希尔记法）: C₃₄H₅₀N₅NaO₇
• 分子量: 663.78
• 分類程式碼代碼: 12352200
• NACRES: NA.28

属性

• 化驗: ≥95% (HPLC)
• 品質等級: 100
• 形狀: lyophilized solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated
• 顏色: white to off-white
• 溶解度: 0.01% NH₄OH: 1 mg/mL; DMSO: 2 mg/mL; methanol: water (3:1): 2 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A highly selective and competitive ETB receptor antagonist (IC₅₀ = 1.2 nM).

Highly selective ET_B-receptor antagonist (IC₅₀ = 1.2 nM).

生化／生理作用

Cell permeable: no

Primary Target
ETB-receptor antagonist

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 1.2 nM as ETB-receptor antagonist

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). DMSO and Methano:H₂O stock solutions are stable for up to 2 months at -20°C.

其他說明

Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53.
Taniai, H., et al. 2001. Hepatology33, 894.
Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461.
Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable