05-1540-M

Anti-Gemin2 Antibody, clone 2E17

clone 2E17, from mouse

• 别名: GEMIN2, Gemin2, Component of gems, SMN interacting protein 1-delta, SMN-interacting protein 1, survival interacting protein 1, survival of motor neuron protein interacting protein
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 2E17, monoclonal
• 物種活性: human
• 物種活性（以同源性預測）: mouse (based on 100% sequence homology)
• 技術: ELISA: suitable; immunocytochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• 同型: IgG1κ
• NCBI登錄號: NM_001009182.1
• UniProt登錄號: O14893
• 目標翻譯後修改: unmodified
• 基因資訊: human ... GEMIN2(8487)

说明

一般說明

Gemin-2 (also known as SIP1 or SMN interacting protein1) is a part of the SMN complex. The SMN complex plays a role in RNA metabolism and in splicing regulation. As part of the SMN complex Gemin-2 interacts directly with Gemin-5 in a heteromeric complex that includes Gemin-3, Gemin-4, Gemin-6. This macromolecular complex (SMN complex) mediates assembly of spliceosomal snRNA complexes containing U1 and U5.

特異性

Antibody recognizes Gemin-2.

免疫原

His-tagged recombinant protein corresponding to human Gemin-2.

應用

Anti-Gemin2 Antibody, clone 2E17 is a Mouse Monoclonal Antibody for detection of Gemin2 also known as SMN interacting protein 1-delta & has been validated in WB, ICC, ELISA & IP.

Immunocytochemistry:
Cited in Battle, D.J., et. al (2007). J. Biol. Chem. 282: 27953 - 27959 and Zhang, Z., et. al (2008). Cell, 133:85-600. using a representative lot.
ELISA:
Cited in Zhang, Z., et. al (2008). Cell, 133:85-600.
Immunoprecipitation:
Cited in Battle, D.J., et. al(2007). J. Biol. Chem. 282: 27953 - 27959 using a representative lot.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Neurodegenerative Diseases

品質

Evaluated by Western Blotting in HeLa cell lysates.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Gemin-2 in HeLa cell lysates.

標靶描述

32 kDa Calculated

外觀

Protein G Purified

Format: Purified

Purified mouse IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
HeLa cell lysates.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable