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Merck
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Key Documents

04-299

Sigma-Aldrich

抗磷酸化胰岛素受体（Tyr 1150/1151）抗体（克隆10C3）

clone 10C3, Upstate®, from mouse

别名:

INSR

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

10C3, monoclonal

物種活性

human

製造商／商標名

Upstate®

技術

activity assay: suitable
western blot: suitable

同型

IgG1

NCBI登錄號

NM_000208.2
NM_001079817.1

UniProt登錄號

P06213

運輸包裝

wet ice

目標翻譯後修改

phosphorylation (pTyr1150/pTyr1151)

基因資訊

human ... INSR(3643)

特異性

可识别胰岛素受体中酪氨酸1150/1151上的磷酸化结构域。

免疫原

KLH偶联的合成肽，对应于磷酸化胰岛素受体上酪氨酸1150/1151周围的氨基酸。

應用

使用经验证可用于EA & WB的该抗磷酸化胰岛素受体（Tyr 1150/1151）抗体（克隆10C3）检测磷酸化胰岛素受体（Tyr 1150/1151）。

品質

已通过免疫印迹进行常规评估。

標靶描述

97kda

外觀

形式：纯化
溶于含0.09%叠氮化钠、PEG、蔗糖和50%甘油的1 mL PBS。

分析報告

对照
包括过钒酸盐处理的HEK293 裂解液作为阳性对照

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

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Natalie N Rizk et al.
Fertility and sterility, 86(4 Suppl), 1217-1222 (2006-09-12)
To determine whether the insulin receptor (IR), insulin-like growth factor-I receptor (IGF-IR), and IGF-I are expressed differentially in fibroblasts isolated from normal peritoneal and adhesion tissue before and after 24-hour treatment with increasing glucose concentrations. Prospective experimental study. University medical
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The FEBS journal, 274(2), 526-538 (2007-01-19)
Two H7721 human hepatocarcinoma cell lines showing moderate and high expression of alpha1,3-fucosyltransferase (FucT)-VII cDNA were established and designated FucTVII-M and FucTVII-H, respectively. In alpha1,3-FucT-VII-transfected cells, expression of insulin receptor (InR) alpha- and beta subunits and epidermal growth factor receptor
Atsumi Tsuji-Hosokawa et al.
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Defects of the insulin receptor gene ( INSR ) cause wide spectra of congenital insulin resistance. Monoallelic defects result in milder insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN, type A). Whereas, leprechaunism (Donahue syndrome), the most severe condition with lethality
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The Journal of biological chemistry, 281(36), 25869-25874 (2006-07-13)
Insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) are both from the same subgroup of receptor tyrosine kinases that exist as covalently bound receptor dimers at the cell surface. For both IR and IGF-IR, the most described forms

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