生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
19G5, monoclonal
物種活性
canine, rat, mouse, human
製造商／商標名
Upstate®
技術
ELISA: suitable
western blot: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
phosphorylation (pTyr1112)
基因資訊
human ... ERBB2(2064)
mouse ... Erbb2(13866)
特異性
Recognizes phosphorylated domain of erbB2/Her2 on Tyrosine 1112
免疫原
KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Tyr1112 in human erbB2/Her2
應用
Detect phosho-erbB2/Her2 (Tyr1112) using this Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5 validated for use in ELISA & WB.
品質
Routinely evaluated by immunoblot.
標靶描述
185 kDa
外觀
Format: Purified
分析報告
Control
Includes EGF treated SKOV-3 lysate as a positive control
Includes EGF treated SKOV-3 lysate as a positive control
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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儲存類別代碼
10 - Combustible liquids
L N Klapper et al.
Cancer research, 60(13), 3384-3388 (2000-07-26)
Overexpression of HER-2/ErbB-2, a homologue of the epidermal growth factor receptor, is associated with poor prognosis, and an ErbB-2-specific antibody is therapeutic when administered to patients with metastatic breast cancer. To understand the mechanism underlying immunotherapy, we concentrated on antibody-
Leonie W Wahjudi et al.
International journal of cancer, 148(6), 1438-1451 (2020-09-20)
DNA sequencing and RNA sequencing are increasingly applied in precision oncology, where molecular tumor boards evaluate the actionability of genetic events in individual tumors to guide targeted treatment. To work toward an additional level of patient characterization, we assessed the
Erin-Mai F Lim et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(9), E1707-E1716 (2017-02-01)
AlphaB-crystallin (αBC) is a small heat shock protein that is constitutively expressed by peripheral nervous system (PNS) axons and Schwann cells. To determine what role this crystallin plays after peripheral nerve damage, we found that loss of αBC impaired remyelination
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