S-043

JWH-019 6-Hydroxyhexyl metabolite solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 别名: JWH-019 6-Hydroxyhexyl metabolite solution
• 经验公式（希尔记法）: C₂₅H₂₅NO₂
• CAS号: 1435934-29-4
• 分子量: 371.47
• EC號碼: 200-659-6
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule E (Switzerland)
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology; forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: OCCCCCCn1cc(C(=O)c2cccc3ccccc23)c4ccccc14
• InChI: 1S/C25H25NO2/c27-17-8-2-1-7-16-26-18-23(21-13-5-6-15-24(21)26)25(28)22-14-9-11-19-10-3-4-12-20(19)22/h3-6,9-15,18,27H,1-2,7-8,16-17H2
• InChI 密鑰: LBVZVDUWOZUDJT-UHFFFAOYSA-N

说明

一般說明

JWH-019 6-Hydroxyhexyl metabolite is a major urinary metabolite of JWH-019, a synthetic cannabinoid found in several blends of the herbal mixture Spice or K2. This biomarker is also referred to as the omega hydroxy metabolite of JWH-019 since the hydroxy group is located at the terminal position of the N-hexyl side chain.

應用

• Advanced Imaging for Synthetic Cannabinoids: JWH-019 has been included in studies utilizing MALDI-MS^3 imaging techniques, which allow for precise spatial characterization of synthetic cannabinoids in biological samples such as single scalp hair. This approach is crucial for forensic toxicology, providing detailed insights into drug distribution and metabolism within tissues (Kernalléguen et al., 2018).


• Metabolite Analysis in Forensic Science: The application of micellar electrokinetic chromatography combined with mass spectrometry for the determination of synthetic cannabinoids like JWH-019 highlights its role in the analytical detection of drug metabolites. This technique is instrumental for both legal and medical investigations, ensuring the accurate identification of synthetic cannabinoid compounds in various matrices (Švidrnoch et al., 2016).


• Quantitative Detection in Serum: JWH-019 has been studied using liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for quantifying synthetic cannabinoids and their metabolites in serum. This method supports clinical and forensic analysis, providing essential data for toxicology reports and therapeutic monitoring (Dresen et al., 2011).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup