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Merck

P-903

Supelco

普罗替林 盐酸盐

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C19H21N · HCl
CAS号:
分子量:
299.84
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

1.0 mg/mL in methanol (as free base)

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

格式

single component solution

儲存溫度

2-8°C

SMILES 字串

CNCCCC1C2=C(C=CC=C2)C=CC3=C1C=CC=C3.[H]Cl

InChI

1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H

InChI 密鑰

OGQDIIKRQRZXJH-UHFFFAOYSA-N

基因資訊

一般說明

Protriptyline is a second generation tricyclic antidepressant (TCA) marketed under the trade name Vivactil®, for treatment of major depression and ADHD. This certified Snap-N-Spike® solution is applicable for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, or urine drug testing. Protriptyline is unique among TCAs, since it has energizing, rather than sedating effects.

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vivactil is a registered trademark of Teva Women's Health, Inc.

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


分析证书(COA)

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T E Wilens et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 35(11), 1485-1490 (1996-11-01)
To evaluate the potential benefit of the tricyclic antidepressant, protriptyline, in the treatment of children and adolescents with attention-deficit hyperactivity disorder (ADHD). All clinic patients in an outpatient pediatric psychopharmacology unit treated with protriptyline for ADHD were monitored for response
J R Wooltorton et al.
British journal of pharmacology, 116(4), 2191-2200 (1995-10-01)
1. The block of K+ currents by amitriptyline and the related tricyclic compounds cyproheptadine and dizocilpine was studied in dissociated rat sympathetic neurones by whole-cell voltage-clamp recording. 2. Cyproheptadine (30 microM) inhibited the delayed-rectifier current (Kv) by 92% and the
Sigrid C Veasey et al.
Sleep, 29(8), 1036-1044 (2006-09-02)
A significant number of patients with obstructive sleep apnea neither tolerate positive airway pressure (PAP) therapy nor achieve successful outcomes from either upper airway surgeries or use of an oral appliance. The purpose of this paper, therefore, was to systematically
M S Hochman et al.
Sleep, 17(3), 280-283 (1994-04-01)
We report the unique occurrence of hyperekplexia and obstructive sleep apnea (OSA) in a 48-year-old male. Polysomnography and multiple sleep latency testing excluded cataplexy, which can be confused with startle attacks. A new imaging finding was a nuclear tomography abnormality
K E Kinnamon et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 216(3), 424-428 (1997-12-24)
Forty-nine "standard" compounds known to be useful in the treatment of other diseases were tested for their suppressive activity against the trypomastigotes of Trypanosoma cruzi-infected mice. The most active was the antidepressant protriptyline, which was almost three times as effective

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