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Merck

L-002

Supelco

LSD-D3 solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

别名:

Lysergic acid diethylamide-D3

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About This Item

经验公式(希尔记法):
C20H22N3OD3
分子量:
326.45
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

濃度

100 μg/mL in acetonitrile

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

forensics and toxicology

格式

single component solution

儲存溫度

2-8°C

SMILES 字串

O=C(N(CC)CC)[C@H]1CN(C([2H])([2H])[2H])[C@](C2=C1)([H])CC3=CNC4=C3C2=CC=C4

InChI

1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1/i3D3

InChI 密鑰

VAYOSLLFUXYJDT-WABLSUFGSA-N

一般說明

LSD, or lysergic acid diethylamide, is an illicit psychedelic drug with potent hallucinogenic effects such as altered thinking processes, closed- and open-eye visuals, synesthesia and an altered sense of time. This internal standard is suitable for LSD testing or isotope dilution methods by GC/MS or LC/MS for urine drug testing, clinical toxicology, or forensic analysis.

應用


  • Hydrocodone-D₃ Analytical Standard Applications: Hydrocodone-D₃ serves as a crucial analytical standard in forensic toxicology, enabling precise quantification and validation of hydrocoDonein biological samples. Its stable isotope-labeled structure is essential for mass spectrometry, providing accurate measurement standards for opioid research and ensuring reliability in legal and clinical settings (Gent et al., 2024).

  • Role in Opioid Research: The compound is instrumental in opioid research, particularly in studying hydrocodone′s pharmacokinetics and dynamics. As a deuterated internal standard, Hydrocodone-D₃ enhances the specificity and sensitivity of assays designed to investigate opioid metabolism and its interactions within the human body (Upadhyay et al., 2024).

  • Biotech Research Chemical Standard: In biotechnology, Hydrocodone-D₃ is used for developing new drug formulations and therapeutic approaches. Its application extends to creating more effective opioid medications with controlled release properties, aimed at reducing dependency and side effects (Senta et al., 2020).

  • Pharmacokinetic Studies: This solution is pivotal in pharmacokinetic studies where researchers assess the absorption, distribution, metabolism, and excretion (ADME) of hydrocodone. By using Hydrocodone-D₃, scientists can track and understand the drug′s behavior in the body more accurately, leading to improved dosing guidelines and safer drug use (Dias Neves et al., 2024).

  • Advancements in Bioanalysis: Hydrocodone-D₃ is also used in advanced bioanalytical research to explore new methodologies for drug testing and monitoring. It acts as a reference point in developing novel detection techniques that are crucial for clinical diagnostics and therapeutic drug monitoring (Zhuang et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

FlameExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

35.6 °F - closed cup

閃點(°C)

2 °C - closed cup


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Justyna McIntyre et al.
The Journal of biological chemistry, 290(45), 27332-27344 (2015-09-16)
Human DNA polymerases (pols) η and ι are Y-family DNA polymerase paralogs that facilitate translesion synthesis past damaged DNA. Both polη and polι can be monoubiquitinated in vivo. Polη has been shown to be ubiquitinated at one primary site. When

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