D-065

脱氢表雄酮3-硫酸钠（DHEAS）标准液 钠盐 溶液

1.0 mg/mL in methanol (as free sulfate), ampule of 1 mL, certified reference material, Cerilliant^®

• 别名: 脱氢表雄酮 3-硫酸盐 钠盐
• 经验公式（希尔记法）: C₁₉H₂₈NaO₅S
• CAS号: 1099-87-2
• 分子量: 391.48
• EC號碼: 200-659-6
• MDL號碼: MFCD00010470
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329798626
• NACRES: NA.24

属性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol (as free sulfate)
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: O=C([C@@]1(C)CC[C@@]23[H])CC[C@]1([C@](CC=C4C[C@H](CC[C@]34C)OS([O-])(=O)=O)2[H])[H].[Na+]
• InChI: 1S/C19H28O5S.Na/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18;/h3,13-16H,4-11H2,1-2H3,(H,21,22,23);/q;+1/p-1/t13-,14-,15-,16-,18-,19-;/m0./s1
• InChI 密鑰: GFJWACFSUSFUOG-ZJTJBYBXSA-M

说明

一般說明

DHEAS是脱氢表雄酮（DHEA）的代谢产物，脱氢表雄酮是一种内源性类固醇，与人类和其他哺乳动物的广泛生物学效应有关。通过LC-MS/MS测量DHEAS水平，以确定在肾上腺癌症、某些形式的先天性肾上腺增生（CAH）和多囊卵巢综合征中观察到的过量肾上腺活性。

應用

• Pharmacokinetic Assessment: Research highlighted the utilization of DHEAS sodium salt in pharmacokinetic studies, exemplified by the development of an LC-MS/MS method to measure Sodium Tanshinone IIA Sulfonate in human plasma. This methodology underscores the role of DHEAS as a critical steroid hormone in biomedicine, enabling precise quantification and study of drug metabolites in clinical settings (Qin et al., 2016).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup