D-053

脱氢阿立哌唑 溶液

1.0 mg/mL in methanol with 5% 1 M HCl, ampule of 1 mL, certified reference material, Cerilliant^®

• 经验公式（希尔记法）: C₂₃H₂₅Cl₂N₃O₂
• CAS号: 129722-25-4
• 分子量: 446.37
• MDL號碼: MFCD00892073
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329798618
• NACRES: NA.24

属性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol with 5% 1 M HCl
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: Clc1cccc(N2CCN(CCCCOc3ccc4C=CC(=O)Nc4c3)CC2)c1Cl
• InChI: 1S/C23H25Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-9,16H,1-2,10-15H2,(H,26,29)
• InChI 密鑰: CDONPRYEWWPREK-UHFFFAOYSA-N

说明

一般說明

脱氢阿立哌唑是阿立哌唑的主要活性代谢产物，作为非典型抗精神病药Abilify^®销售，用于精神分裂症，双相障碍和临床抑郁的治疗。这种新的认证溶液标准品适用于LC或GC应用，包括法医或临床毒理学分析和尿液药物测试。

應用

• Fostering the unleashing potential of nanocarriers-mediated delivery of ocular therapeutics: This review discusses the critical role of Cyclosporin A in the development of nanocarrier systems for targeted drug delivery, particularly for ocular applications. Cyclosporin A′s effectiveness in preventing transplant rejection and its properties as a calcineurin inhibitor make it an excellent candidate for incorporation into advanced drug delivery systems, enhancing therapeutic efficacy and reducing systemic side effects (Datta D et al., 2024).

法律資訊

Abilify is a registered trademark of Otsuka Pharmaceutical Co.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS06,GHS08,GHS05
• 訊號詞: Danger
• 危險聲明: H225,H290,H301 + H311 + H331,H370
• 防範說明: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Met. Corr. 1 - STOT SE 1
• 標靶器官: Eyes,Central nervous system
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 51.8 °F - closed cup
• 閃點（°C）: 11 °C - closed cup