推荐产品
等級
certified reference material
品質等級
形狀
liquid
特點
Snap-N-Spike®/Snap-N-Shoot®
包裝
ampule of 1 mL
製造商／商標名
Cerilliant®
濃度
1.0 mg/mL in methanol
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
clinical testing
clinical testing
格式
single component solution
儲存溫度
−20°C
SMILES 字串
CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO
InChI
1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChI 密鑰
OMFXVFTZEKFJBZ-HJTSIMOOSA-N
一般說明
皮质酮是在肾上腺中产生的皮质类固醇和醛固酮前体。通过LC-MS/MS测量血清皮质酮水平，以筛查新生儿和诊断11-羟化酶缺乏症。
應用
- Corticosterone ELISA kit for stress hormone research: Research has demonstrated the efficacy of corticosterone ELISA kits in measuring stress hormone levels, contributing significantly to studies on adrenal gland function and stress-related disorders. This application is vital for in vivo corticosterone analysis, allowing detailed monitoring of hormone fluctuations in response to various stressors (Ornelas et al., 2024).
- High-purity corticosterone for receptor binding assays: Corticosterone solutions are extensively used in receptor binding assays to understand corticosteroid receptor interactions. These studies are crucial for advancing knowledge in endocrinology biochemical studies, particularly in mapping corticosteroid pathways and their effects within the body (Xie et al., 2024).
- Synthetic corticosterone solution for endocrine studies: Synthetic corticosterone is employed in clinical experimental setups to examine the endocrine system′s response under controlled conditions. This usage is particularly evident in studies focusing on the adaptation of the endocrine system to external stress factors and its impact on overall physiological health (Costa et al., 2024).
- Liquid corticosterone for stress response research: Liquid formulations of corticosterone are pivotal in conducting stress response research, providing a consistent and measurable means of administering this hormone to study its acute and chronic effects on animal behavior and physiological responses (Ornelas et al., 2023).
- Corticosterone reagent for glucocorticoid receptor experiments: As a reagent, corticosterone is integral to glucocorticoid receptor experiments, which are essential for understanding glucocorticoid receptor dynamics and their implications in various physiological processes, including immune response and metabolic regulation (Heraudeau et al., 2023).
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相關產品
产品编号
说明
价格
氢化可的松-D4标准液 CRM 溶液, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
11-脱氧皮质醇-D5标准液 CRM, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
17α-羟孕酮-13C3标准液 溶液, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
49.5 °F - closed cup
閃點（°C）
9.7 °C - closed cup
其他客户在看
T Shavlakadze et al.
American journal of physiology. Cell physiology, 305(1), C26-C35 (2013-04-19)
Circadian rhythms and metabolism are tightly integrated, and rhythmic expression of metabolic factors is common in homeostatic processes. We measured the temporal changes in the expression of myogenic regulatory factors and expression and activity level of molecules involved in protein
N E Ordian et al.
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 63(2), 280-289 (2013-07-23)
Anxious-depressive state was studied in experimental "stress-restress" model of posttraumatic stress disorder (PTSD) using adult rat males. Rat males were born by control females and whose mothers were under 60-minute immobilization stress since 15 until 19 days of pregnancy. Then
Krzysztof Gil et al.
Neuro endocrinology letters, 34(4), 314-321 (2013-06-28)
The brain and the gut communicate bi-directionally through the brain-gut axis. The key role in such interactions plays autonomic nervous system and its major component, the vagus nerve. There is growing evidence that vagus nerve stimulation (VNS) has a suppressive
L J F van de Ven et al.
Poultry science, 92(4), 1050-1061 (2013-03-09)
Little is known about physiological responses of early- versus late-hatching chicks to early posthatch conditions in broiler practice. We investigated effects of hatching time on perinatal broiler physiology in 2 hatching systems, differing in conditions: a conventional hatcher, where chicks
T V Shemenkova et al.
Bulletin of experimental biology and medicine, 154(4), 464-466 (2013-03-15)
ACTH1-24(1 mg/kg) administered to 5-7-day-old rats reduced their locomotor activity and did not alter blood levels of corticosterone. ACTH administration on postnatal days 12-14 increased corticosterone levels, but had no effect on locomotor activity. Thus, the behavioral effect of ACTH
实验方案
The conversion of clinical methods to LC/MS/MS offers advantages; however, is accompanied by a few limitations, notably interference effects from the endogenous sample matrix.
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