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LM4113

Avanti

25-hydroxycholesterol (D6)

Avanti Polar Lipids LM4113, methanol solution

别名:

cholest-5-ene-3β,25-diol(d6)

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About This Item

经验公式（希尔记法）:
C27H40D6O2
CAS号:
88247-69-2
分子量:
408.69
分類程式碼代碼:
12352100
NACRES:
NA.25

形狀

methanol solution

包裝

pkg of 1 × 1 mL (LM4113-1EA)

製造商／商標名

Avanti Polar Lipids LM4113

濃度

~10 μg/mL (Refer to C of A for lot specific concentration. )

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(O)(C([2H])([2H])[2H])C([2H])([2H])[2H]

相关类别

一般說明

25-hydroxycholesterol is an oxygenated sterol and a hydroxylated derivative of cholesterol.

生化／生理作用

25-hydroxycholesterol inhibits cholesterol biosynthesis by downregulating the function of 3-hydroxy-3-methylglutaryl-CoA reductase. It is found to be implicated in atherosclerosis. 25-hydroxycholesterol levels are known to be increased in hypercholesterolemic condition.

包裝

2 mL Amber Glass Sealed Ampule (LM4113-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析证书(COA)

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Christopher M Adams et al.
The Journal of biological chemistry, 279(50), 52772-52780 (2004-09-29)
The current paper demonstrates that cholesterol and its hydroxylated derivative, 25-hydroxycholesterol (25-HC), inhibit cholesterol synthesis by two different mechanisms, both involving the proteins that control sterol regulatory element-binding proteins (SREBPs), membrane-bound transcription factors that activate genes encoding enzymes of lipid

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