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Merck

LM1202

Avanti

17:0-20:4 PG

Avanti Research - A Croda Brand

别名:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-rac-glycerol) (ammonium salt)

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About This Item

经验公式(希尔记法):
C43H80NO10P
分子量:
802.07
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

methanol solution

包裝

pkg of 1 × 1 mL (LM1202-1EA)

製造商/商標名

Avanti Research - A Croda Brand

濃度

~10 μg/mL (Refer to C of A for lot specific concentration.)

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

一般說明

Phosphatidylglycerol (PG) is mostly found in the pulmonary surfactant and localized to the alveoli.

應用

17:0-20:4 PG or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-rac-glycerol):
  • has been used as an internal standard (IS) in lipid extraction from isolated pure mitochondria for mass spectrometry (MS) analysis
  • has been used as an internal standard (IS) in liquid chromatography (LC)-MS analysis
  • might be used in dual substrate (acyl-CoA and lysophospholipid) choice acyltransferase assay
  • might be used for quantitative phospholipid analysis by MS

生化/生理作用

Phosphatidylglycerol (PG) is known to be involved in the inflammatory mechanism and offers protection against viral infection.

包裝

2 mL Amber Glass Sealed Ampule (LM1202-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


分析证书(COA)

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访问文档库

Christoph Potting et al.
Cell metabolism, 18(2), 287-295 (2013-08-13)
Cardiolipin (CL), a mitochondria-specific glycerophospholipid, is required for diverse mitochondrial processes and orchestrates the function of various death-inducing proteins during apoptosis. Here, we identify a complex of the p53-regulated protein TRIAP1 (p53CSV) and PRELI in the mitochondrial intermembrane space (IMS)
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the

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