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Merck

860667P

Avanti

4E,8Z-Sphingadiene

Avanti Research - A Croda Brand 860667P, powder

别名:

(2S,3R,4E,8Z)-2-aminooctadec-4,8-diene-1,3-diol

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About This Item

经验公式(希尔记法):
C18H35NO2
CAS号:
分子量:
297.48
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 1 mg (860667P-1mg)

製造商/商標名

Avanti Research - A Croda Brand 860667P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@@](N)([H])[C@]([H])(O)/C=C/CC/C=C\CCCCCCCCC

一般說明

4E,8Z-Sphingadiene is a unique sphingoid base containing C18 chain, with trans double bond at C-4 and cis double bond at C8. It is widely present in plant tissues, but very minimal in mammals.

應用

4E,8Z-Sphingadiene has been used as an standard in liquid chromatography with tandem mass spectrometry (LC-MS-MS) method for quantitation of chemopreventive sphingadienes in food products and biological samples.

生化/生理作用

Sphingadienes are growth-inhibitory sphingoid bases, which play a vital role in apoptosis and cell signaling. Sphingadienes isolated from plants exhibit anti-inflammatory properties by inhibiting tumor necrosis factor α (TNF α) activity.

包裝

5 mL Amber Glass Screw Cap Vial (860667P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

No data available

閃點(°C)

No data available


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O Renkonen et al.
Journal of lipid research, 10(6), 687-693 (1969-11-01)
The dienic long-chain base (sphingadienine) of human plasma sphingomyelins has been identified as d-erythro-1,3-dihydroxy-2-amino-4-trans-14-cis-octadecadiene. A similar sphingosine was also detected in plasma sphingomyelins of rat, rabbit, and cat. The key reaction in the structural studies was partial reduction of sphingadienine
Occurrence, structure elucidation, biosynthesis, functions and synthesis of sphingadienes
U Abeytunga T
Mini-Reviews in Organic Chemistry, 12(3), 282-292 (2015)
Structural analysis of unsaturated glycosphingolipids using shotgun ozone-induced dissociation mass spectrometry
Barrientos RC, et al.
Journal of the American Society For Mass Spectrometry, 28(11), 2330-2343 (2017)

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