推荐产品
形狀
powder
包裝
pkg of 1 × 10 mg (860645P-10mg)
製造商／商標名
Avanti Research™ - A Croda Brand 860645P
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCC
InChI
1S/C25H49NO3/c1-3-5-7-9-10-11-12-13-14-15-17-18-20-24(28)23(22-27)26-25(29)21-19-16-8-6-4-2/h18,20,23-24,27-28H,3-17,19,21-22H2,1-2H3,(H,26,29)/b20-18+/t23-,24+/m0/s1
一般說明
C8-ceramide or N-octanoyl-D-erythro-sphingosine (C17 base) is a synthetic cell-permeable sphingolipid. It is a combination of C17 analog of sphingosine and octanoic acid. Ceramides are the major lipid component in the outermost layer of the skin, the stratum corneum. C8 Ceramide plays a vital role in inducing apoptotic cell death.
應用
C8 Ceramide (d17:1/8:0) has been used to induce myriocin-treated malignant melanoma cells to increase endogenous ceramide levels.
包裝
5 mL Amber Glass Screw Cap Vial (860645P-10mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Y-S Lee et al.
Cell proliferation, 44(4), 320-329 (2011-06-08)
Melanoma is the most aggressive form of skin cancer, and it resists chemotherapy. Candidate drugs for effective anti-cancer treatment have been sought from natural resources. Here, we have investigated anti-proliferative activity of myriocin, serine palmitoyltransferase inhibitor, in the de novo
J P Witty et al.
Endocrinology, 137(12), 5269-5277 (1996-12-01)
Recent studies have demonstrated that ovarian follicle atresia occurs extensively before follicle selection into the avian preovulatory hierarchy, and that this process is mediated via granulosa cell apoptosis. Subsequent to follicle selection, granulosa cells are inherently resistant to apoptosis, and
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