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860530P

Avanti

C2 1-磷酸神经酰胺（d18：1/2：0）

N-acetoyl-ceramide-1-phosphate (ammonium salt), powder

别名:

(2S,3R,4E)?2?acetoylaminooctadec?4?ene?1,3?diol?1?磷酸盐（胺盐）

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About This Item

经验公式（希尔记法）:
C20H43N2O6P
CAS号:
474943-68-5
分子量:
438.54
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 1 mg (860530P-1mg)

製造商／商標名

Avanti Research™ - A Croda Brand 860530P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(C)=O)COP([O-])(O)=O.[NH4+]

InChI

1S/C20H40NO6P.H3N/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(23)19(21-18(2)22)17-27-28(24,25)26;/h15-16,19-20,23H,3-14,17H2,1-2H3,(H,21,22)(H2,24,25,26);1H3/b16-15+;/t19-,20+;/m0./s1

InChI 密鑰

RLNAXSSXIQXSCV-AQCNXKLSSA-N

相关类别

應用

C2神经酰胺-1-磷酸酯（d18:1/2:0）或N-乙酰基-神经酰胺-1-磷酸酯已用于筛选快速可逆地改变跨上皮电阻（TER）或紧密连接（TJ）渗透性的脂质在上皮组织中。它也已用于研究其在发育或灰葡萄孢感染过程中在野生和acd5植物中的积累动力学。

包裝

5 mL棕色玻璃螺旋盖小瓶（860530P-1mg）

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

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V T Hinkovska-Galcheva et al.
The Journal of biological chemistry, 273(50), 33203-33209 (1998-12-05)
Ceramide, a product of agonist-stimulated sphingomyelinase activation, is known to be generated during the phagocytosis of antibody-coated erythrocytes by polymorphonuclear leukocytes. Agonist-stimulated formation of ceramide-1-phosphate is now shown to occur in 32PO4-labeled neutrophils. Ceramide-1-phosphate is formed by a calcium-dependent ceramide
Antonio Gómez-Muñoz et al.
Journal of lipid research, 45(1), 99-105 (2003-10-03)
It was reported previously that ceramide-1-phosphate (Cer-1-P) is mitogenic for fibroblasts (Gómez-Muñoz, A., P. A. Duffy, A. Martin, L. O'Brien, H-S. Byun, R. Bittman, and D. N. Brindley. 1995. Mol. Pharmacol. 47: 883-889; Gómez-Muñoz, A., L. M. Frago, L. Alvarez
A Gomez-Muñoz et al.
Molecular pharmacology, 47(5), 833-839 (1995-05-01)
Ceramide and ceramide-1-phosphate are sphingolipid analogues of diacylglycerol and phosphatidate, respectively, and they are putative second messengers of agonist-stimulated sphingomyelin metabolism. The interactions of exogenous cell-permeable ceramides and ceramide-1-phosphates in modifying DNA synthesis and signal transduction were investigated in Rat-1

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