860526P

1-O-Acyl-Ceramide

Avanti Research^™ - A Croda Brand 860526P, powder

• 别名: 1-oleoyl-N-heptadecanoyl-D-erythro-sphingosine
• 经验公式（希尔记法）: C₅₃H₁₀₁NO₄
• CAS号: 1246303-19-4
• 分子量: 816.37
• 分類程式碼代碼: 12352211
• NACRES: NA.25

属性

• 形狀: powder
• 包裝: pkg of 1 × 5 mg (860526P-5mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 860526P
• 脂質類型: sphingolipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
• InChI: 1S/C53H101NO4/c1-4-7-10-13-16-19-22-25-27-30-33-36-39-42-45-48-53(57)58-49-50(51(55)46-43-40-37-34-31-28-24-21-18-15-12-9-6-3)54-52(56)47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25,27,43,46,50-51,55H,4-24,26,28-42,44-45,47-49H2,1-3H3,(H,54,56)/b27-25-,
• InChI 密鑰: FRBOSLBQGQIWQM-YXQBTRHCSA-N

说明

一般說明

1-O-Acyl-Ceramide is an epidermal ceramide present in mouse and human epidermis. It comprises long chain fatty acids in 1-O-position and is synthesized in the endoplasmic reticulum-related sites.

應用

1-O-Acyl-Ceramide is suitable for use as a lipid standard in

• high performance thin layer chromatography (HPTLC)
• in mass and nuclear magnetic resonance spectroscopy for the quantification of lipids isolated from vernix caseosa skin cream
• in liquid chromatography-tandem mass spectrometry for the quantification of 1-O-Acyl ceramides from liver samples

生化／生理作用

1-O-Acyl-Ceramide functions in maintaining water barrier homeostasis. Deficiency of the glucosylceramide synthase enzyme leads to the accumulation of O-acylceramides. Treatment of human monoclonal antibody, REMD 2.59 leads to the accumulation of 1-O-acyl-ceramides in soleus muscle and depletion in liver.

包裝

5 mL Amber Glass Screw Cap Vial (860526P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3