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形狀
powder
包裝
pkg of 1 × 10 mg (860498P-10mg)
pkg of 1 × 100 mg (860498P-100mg)
pkg of 1 × 25 mg (860498P-25mg)
製造商／商標名
Avanti Research™ - A Croda Brand
脂質類型
sphingolipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
InChI
1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
InChI 密鑰
OTKJDMGTUTTYMP-ZWKOTPCHSA-N
一般說明
鞘氨醇（d18:0）是神经酰胺去饱和酶的底物。它是由于补充的甘氨酸向丝氨酸的相互转化而间接合成的。鞘氨醇（d18:0）分解代谢为神经酰胺。
應用
鞘氨醇（d18:0）已用于：
- 作为标准品，利用液相色谱-串联质谱法定量表皮神经酰胺
- 作为培养基补充，检测其对酵母细胞生长的效应
- 制备牛血清白蛋白脂质复合物，研究其对非溶酶体-葡萄糖基神经酰胺酶β2（GBA2）抑制作用的效应
生化／生理作用
鞘氨醇（d18:0）的水平在1型遗传性感觉神经病细胞中没有改变。在肿瘤缺氧中观察到d18:0的积累。它可用作研究微生物多样性的生物标记物。
包裝
5 mL棕色玻璃螺旋盖小瓶（860498P-100mg）
5 mL棕色玻璃螺旋盖小瓶（860498P-10mg）
5 mL棕色玻璃螺旋盖小瓶（860498P-25mg）
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Altered sphingolipid metabolism induced by tumor hypoxia-new vistas in glycolipid tumor markers
Yin J, et al.
Febs Letters, 584(9), 1872-1878 (2010)
Sunyoung Hwang et al.
Cell reports, 29(8), 2473-2488 (2019-11-21)
An abnormal number of chromosomes, or aneuploidy, accounts for most spontaneous abortions, causes developmental defects, and is associated with aging and cancer. The molecular mechanisms by which aneuploidy disrupts cellular function remain largely unknown. Here, we show that aneuploidy disrupts
Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development
Wang Z, et al.
The Journal of Investigative Dermatology, 133(3), 668-676 (2013)
Identification of a feedback loop involving beta-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease
Schonauer S, et al.
Test, 292(15), 6177-6189 (2017)
Tingting Qin et al.
Nucleic acids research, 42(18), e138-e138 (2014-07-27)
To enhance our knowledge regarding biological pathway regulation, we took an integrated approach, using the biomedical literature, ontologies, network analyses and experimental investigation to infer novel genes that could modulate biological pathways. We first constructed a novel gene network via
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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